Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.
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Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domainAssociation of insulin receptor substrate 1 with simian virus 40 large T antigenThe phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptorDistinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domainsCharacterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)Tyrosine kinase signalling in breast cancer: tyrosine kinase-mediated signal transduction in transgenic mouse models of human breast cancer.beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosisSignaling via Shc family adapter proteinsThe intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid systemShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation.ShcA tyrosine phosphorylation sites can replace ShcA binding in signalling by middle T-antigenSequence requirements for binding of Src family tyrosine kinases to activated growth factor receptorsShcA signalling is essential for tumour progression in mouse models of human breast cancerPhosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformationShc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIPSystematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factorA Transformation-Defective Polyomavirus Middle T Antigen with a Novel Defect in PI3 Kinase Signaling.Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous Viral RNA EditingPolyomavirus middle-T antigen associates with the kinase domain of Src-related tyrosine kinases.Deregulation of the Hippo pathway in mouse mammary stem cells promotes mammary tumorigenesis.Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivoPKN binds and phosphorylates human papillomavirus E6 oncoprotein.Catalytically inactive protein phosphatase 2A can bind to polyomavirus middle tumor antigen and support complex formation with pp60(c-src).Middle T antigen activation of signal transduction pathways does not overcome p53-mediated growth arrest.Phosphatidylinositol 3-kinase binding to polyoma virus middle tumor antigen mediates elevation of glucose transport by increasing translocation of the GLUT1 transporter.Mechanisms of cell transformation induced by polyomavirus.Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteinsDisruption of the Shc/Grb2 complex during abelson virus transformation affects proliferation, but not apoptosis.Signal transduction in mammary tumorigenesis: a transgenic perspective.Natural biology of polyomavirus middle T antigen.Accelerated mammary tumor development in mutant polyomavirus middle T transgenic mice expressing elevated levels of either the Shc or Grb2 adapter protein.Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis.Cell transformation by the middle T-antigen of polyoma virus.Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus.Transgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma.Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.Independent contributions of polyomavirus middle T and small T to the regulation of early and late gene expression and DNA replicationSH2 and PTB domains in tyrosine kinase signaling.A new class of mutations reveals a novel function for the original phosphatidylinositol 3-kinase binding site.
P2860
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P2860
Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Polyoma middle tumor antigen i ...... motif in middle tumor antigen.
@ast
Polyoma middle tumor antigen i ...... motif in middle tumor antigen.
@en
type
label
Polyoma middle tumor antigen i ...... motif in middle tumor antigen.
@ast
Polyoma middle tumor antigen i ...... motif in middle tumor antigen.
@en
prefLabel
Polyoma middle tumor antigen i ...... motif in middle tumor antigen.
@ast
Polyoma middle tumor antigen i ...... motif in middle tumor antigen.
@en
P2093
P2860
P356
P1476
Polyoma middle tumor antigen i ...... motif in middle tumor antigen
@en
P2093
B J Druker
B S Schaffhausen
D C Pallas
K S Campbell
T M Roberts
P2860
P304
P356
10.1073/PNAS.91.14.6344
P407
P50
P577
1994-07-01T00:00:00Z