Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA - Wikidata - wikimedia - TriplyDB

Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA

Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA

http://www.wikidata.org/entity/Q28360244

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Base Excision Repair, a Pathway Regulated by Posttranslational Modifications Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage A quantitative model of human DNA base excision repair. I. Mechanistic insights.DNA polymerase beta-dependent long patch base excision repair in living cells.Excision of a lyase-resistant oxidized abasic lesion from DNA.Repair of single-strand DNA interruptions by redundant pathways and its implication in cellular sensitivity to DNA-damaging agents Specific Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases.Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: possible implication for the pathogenesis of immotile cilia syndrome.Mammalian base excision repair: the forgotten archangel Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis.Metabolism, genomics, and DNA repair in the mouse aging liver.Disruption of PARP1 function inhibits base excision repair of a sub-set of DNA lesions The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta in long patch base excision repair Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice.Comparative assessment of plasmid and oligonucleotide DNA substrates in measurement of in vitro base excision repair activity.Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis.Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks Base excision repair in physiology and pathology of the central nervous system The involvement of DNA-damage and -repair defects in neurological dysfunction Evidence for base excision repair processing of DNA interstrand crosslinks.Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1 R152C DNA Pol β mutation impairs base excision repair and induces cellular transformation A novel function of adenomatous polyposis coli (APC) in regulating DNA repair.Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.Strand displacement synthesis by yeast DNA polymerase ε.An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda.Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells.Futile short-patch DNA base excision repair of adenine:8-oxoguanine mispair.A DNA polymerase beta mutant from colon cancer cells induces mutations.Base excision repair targets for cancer therapy Oxidized base damage and single-strand break repair in mammalian genomes: role of disordered regions and posttranslational modifications in early enzymes.DNA repair mechanisms in Huntington's disease.Monitoring regulation of DNA repair activities of cultured cells in-gel using the comet assay.The impact of base excision DNA repair in age-related neurodegenerative diseases Assembly of the base excision repair complex on abasic DNA and role of adenomatous polyposis coli on its functional activity.Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair.

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Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA

http://www.wikidata.org/entity/Q28360244

description

2001 nî lūn-bûn

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2001 թուականի Մարտին հրատարակուած գիտական յօդուած

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2001 թվականի մարտին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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Human DNA polymerase beta init ...... air of reduced AP sites in DNA

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Human DNA polymerase beta init ...... air of reduced AP sites in DNA

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Human DNA polymerase beta init ...... air of reduced AP sites in DNA

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Human DNA polymerase beta init ...... air of reduced AP sites in DNA

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Human DNA polymerase beta init ...... air of reduced AP sites in DNA

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prefLabel

Human DNA polymerase beta init ...... air of reduced AP sites in DNA

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Human DNA polymerase beta init ...... air of reduced AP sites in DNA

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Human DNA polymerase beta init ...... air of reduced AP sites in DNA

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The EMBO Journal

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Human DNA polymerase beta init ...... air of reduced AP sites in DNA

@en

P2093

A J Podlutsky

http://www.w3.org/2001/XMLSchema#string

G L Dianov

http://www.w3.org/2001/XMLSchema#string

I I Dianova

http://www.w3.org/2001/XMLSchema#string

V A Bohr

http://www.w3.org/2001/XMLSchema#string

V N Podust

http://www.w3.org/2001/XMLSchema#string

P2860

Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon

Instability and decay of the primary structure of DNA

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

Rate of depurination of native deoxyribonucleic acid

Quality control by DNA repair

Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair

Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells.

DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

Repair of intrinsic DNA lesions.

Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair.

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1477-82

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scholarly article

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4761018

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10.1093/EMBOJ/20.6.1477

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P433

6

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20

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2001-03-15T00:00:00Z

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247445856

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11250913

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145539

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