Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules
about
Human immunodeficiency virus type 1 preintegration complexes: studies of organization and compositionStructure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug designStructure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitorHuman immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes.Specific inhibition of human immunodeficiency virus type 1 (HIV-1) integration in cell culture: putative inhibitors of HIV-1 integraseResistance to the anti-human immunodeficiency virus type 1 compound L-chicoric acid results from a single mutation at amino acid 140 of integraseHuman immunodeficiency virus type 1 cDNA integration: new aromatic hydroxylated inhibitors and studies of the inhibition mechanism.Isolation and characterization of novel human immunodeficiency virus integrase inhibitors from fungal metabolitesDicaffeoylquinic and dicaffeoyltartaric acids are selective inhibitors of human immunodeficiency virus type 1 integrase.Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compoundsInhibition of acute-, latent-, and chronic-phase human immunodeficiency virus type 1 (HIV-1) replication by a bistriazoloacridone analog that selectively inhibits HIV-1 transcriptionIntegration complexes derived from HIV vectors for rapid assays in vitro.Targeting Tn5 transposase identifies human immunodeficiency virus type 1 inhibitors.Homogeneous high-throughput screening assays for HIV-1 integrase 3beta-processing and strand transfer activities.Irreversible inhibition of human immunodeficiency virus type 1 integrase by dicaffeoylquinic acids.Modulation of activity of Moloney murine leukemia virus preintegration complexes by host factors in vitro.Structure-based HIV-1 integrase inhibitor design: a future perspective.Inhibition of human immunodeficiency virus type 1 integration by diketo derivativesRetroviral integrase proteins and HIV-1 DNA integrationIn search of authentic inhibitors of HIV-1 integration.Computational investigation of the anti-HIV activity of Chinese medicinal formula Three-Huang Powder.Prediction of the interaction of HIV-1 integrase and its dicaffeoylquinic acid inhibitor through molecular modeling approachTargeting HIV-1 integrase.Development of a human immunodeficiency virus vector-based, single-cycle assay for evaluation of anti-integrase compoundsHIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase.Nuclear import of the preintegration complex is blocked upon infection by human immunodeficiency virus type 1 in mouse cells.Single-particle image reconstruction of a tetramer of HIV integrase bound to DNA.Tethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites.Human immunodeficiency virus type 2 preintegration complexes: activities in vitro and response to inhibitors.Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases.Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions.Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors.HIV-1 preintegration complexes preferentially integrate into longer target DNA molecules in solution as detected by a sensitive, polymerase chain reaction-based integration assay.Activity of recombinant HIV-1 integrase on mini-HIV DNA.Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives.Identification of critical amino acid residues in human immunodeficiency virus type 1 IN required for efficient proviral DNA formation at steps prior to integration in dividing and nondividing cells.Differential divalent cation requirements uncouple the assembly and catalytic reactions of human immunodeficiency virus type 1 integrase.Identification of HIV-1 integrase inhibitors based on a four-point pharmacophore.Aromatic Medicinal Plants from Tajikistan (Central Asia).Mechanistic and pharmacological analyses of HIV-1 integration.
P2860
Q24673418-BBBC67FF-9EC8-49B0-A65C-67D4BD6F4350Q27620348-9CE83E7E-50A5-4163-A046-5A18067235AEQ27749615-CDF805E0-175C-420E-B872-737C019DE094Q28343322-3637807C-7FAE-46FA-A1AF-2A50ED1A00F0Q28345957-02BDF300-9644-4142-8450-22E0800BCBF1Q28368842-92446B6E-0465-4C2D-85B5-D8B6A990D12DQ28368861-BA406D82-8EFD-40EB-95AD-6111621DDBCFQ28376469-6F8E2910-3B7F-417C-9AF7-DF1B5CFB622AQ28379316-B3EB25C5-1B06-4A40-B3E0-0E573C276852Q28379401-FBE4FD1C-7CDA-4A23-BCED-FDDEAF58E17EQ28379402-885134C5-9899-4CE0-8A2D-9A0025D758E1Q30724955-D2753572-3E53-4CC1-A01E-EB1873951778Q31164008-0153988A-D552-4F74-8683-082118373F6FQ33221506-6334D40C-8823-4ADD-8457-AB8518125B47Q33645102-C63F6B39-3165-4B4E-87A9-3D7361CB1435Q33782399-D8897521-953D-4905-AC0F-7E4E77375DFAQ34141071-7BE3B2E8-7C4C-4F25-B0A9-6AA071FE094EQ34143182-2B9009BA-846B-433F-B6BC-693A10E98B61Q34643561-BA5537F1-9868-4D80-935D-E54F3CBADD61Q34785977-84D6705A-F2AD-4379-895A-1830B028C090Q34854675-EDD55772-9562-4582-8D64-9A7877926C49Q34952453-AAA5B496-BD9E-41FD-9F01-CCF158B777E7Q35050390-E4593881-75D7-4C36-B5F1-FE3F746046FEQ35091567-5A1AA896-641D-45BD-B3E2-EE67C547110CQ35267783-A08CE594-419F-4C89-B6E8-7D607C1E26CAQ35635000-7740A293-CC1B-4D0D-81FE-979CD7A39F41Q35757779-BF0D9A8D-9502-4458-B58F-35993655EEA6Q35875075-5BCF0C77-14F3-4850-9C87-3B10211A0B84Q35882060-451680C5-10DD-4947-8A4C-58090024B147Q36928605-012B2FFB-5D18-4840-A727-FDFE56D973C2Q37009146-DBB62DC8-31D4-44BF-B2FE-6AB00FF8E925Q37399117-D00F8BE7-FB0D-421F-BA45-1AE42FBAA4A6Q38295884-6E4FE6DB-5440-4404-9DB9-A12EB1D1B088Q38325390-42153A0B-2C4F-4178-8A02-52AA9343D803Q38746848-445D3DF9-FD66-4704-9743-D7D94AB0613FQ39591194-3BB0AAEF-C1CC-49C4-A100-19BD15858839Q39881008-322F2D63-916F-45B6-82A4-833B6A16B759Q40985936-975838DF-46D8-472B-B41F-745ECC23E7FFQ41165653-A3B260AA-FAE9-4AF7-B4C0-33434E683F38Q41963850-D9E12F73-B18B-46E0-8F21-86CACDF1C10A
P2860
Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules
description
1996 nî lūn-bûn
@nan
1996 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Differential inhibition of HIV ...... ase protein by small molecules
@ast
Differential inhibition of HIV ...... ase protein by small molecules
@en
Differential inhibition of HIV ...... ase protein by small molecules
@nl
type
label
Differential inhibition of HIV ...... ase protein by small molecules
@ast
Differential inhibition of HIV ...... ase protein by small molecules
@en
Differential inhibition of HIV ...... ase protein by small molecules
@nl
prefLabel
Differential inhibition of HIV ...... ase protein by small molecules
@ast
Differential inhibition of HIV ...... ase protein by small molecules
@en
Differential inhibition of HIV ...... ase protein by small molecules
@nl
P2093
P2860
P356
P1476
Differential inhibition of HIV ...... ase protein by small molecules
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.18.9742
P407
P577
1996-09-03T00:00:00Z