Tethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites.
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Human immunodeficiency virus type 1 preintegration complexes: studies of organization and compositionIntracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatinBioinformatic analysis of HIV-1 entry and pathogenesis.Retroviral vectors and transposons for stable gene therapy: advances, current challenges and perspectivesProtein determinants of insertional specificity for the Drosophila gypsy retrovirusDriving DNA transposition by lentiviral protein transductionChromosome structure and human immunodeficiency virus type 1 cDNA integration: centromeric alphoid repeats are a disfavored target.Revealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteinsIntegration site selection by retroviral vectors: molecular mechanism and clinical consequences.Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic proteinLEDGF hybrids efficiently retarget lentiviral integration into heterochromatin.A chimeric Ty3/Moloney murine leukemia virus integrase protein is active in vivo.Integrase-lexA fusion proteins incorporated into human immunodeficiency virus type 1 that contains a catalytically inactive integrase gene are functional to mediate integrationMethods for integration site distribution analyses in animal cell genomesSubtype-associated differences in HIV-1 reverse transcription affect the viral replication.Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cellsIntegration by design.Controlling integration specificity of a yeast retrotransposonCurrent advances in retroviral gene therapy.Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sitesSite-directed transposon integration in human cells.Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy.The role of lysine 186 in HIV-1 integrase multimerizationRetargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains.Sites of retroviral DNA integration: From basic research to clinical applicationsTargeted, homology-driven gene insertion in stem cells by ZFN-loaded 'all-in-one' lentiviral vectors.Analysis of viral and cellular proteins in HIV-1 reverse transcription complexes by co-immunoprecipitation.Delivering factors for reprogramming a somatic cell to pluripotencyRetargeted Foamy Virus Vectors Integrate Less Frequently Near Proto-oncogenes.Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleasesGenotoxicity of retroviral hematopoietic stem cell gene therapy.Viral hybrid vectors for somatic integration - are they the better solution?Precise targeted integration by a chimaeric transposase zinc-finger fusion protein.Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase.rDNA-directed integration by an HIV-1 integrase--I-PpoI fusion proteinHIV-1 integrase sequence variability in antiretroviral naïve patients and in triple-class experienced patients subsequently treated with raltegravir.Relative Comparison of Catalytic Characteristics of Human Foamy Virus and HIV-1 Integrases.Mechanistic and pharmacological analyses of HIV-1 integration.
P2860
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P2860
Tethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Tethering human immunodeficien ...... s integration at nearby sites.
@ast
Tethering human immunodeficien ...... s integration at nearby sites.
@en
type
label
Tethering human immunodeficien ...... s integration at nearby sites.
@ast
Tethering human immunodeficien ...... s integration at nearby sites.
@en
prefLabel
Tethering human immunodeficien ...... s integration at nearby sites.
@ast
Tethering human immunodeficien ...... s integration at nearby sites.
@en
P2860
P1433
P1476
Tethering human immunodeficien ...... s integration at nearby sites.
@en
P2093
F D Bushman
M D Miller
P2860
P304
P407
P577
1997-01-01T00:00:00Z