about
Systems Pharmacology in Small Molecular Drug DiscoverySystems pharmacology: network analysis to identify multiscale mechanisms of drug actionA survey on the computational approaches to identify drug targets in the postgenomic eraSTITCH 4: integration of protein-chemical interactions with user dataIdentification of candidate small-molecule therapeutics to cancer by gene-signature perturbation in connectivity mappingPrediction of drug combinations by integrating molecular and pharmacological dataNetwork neighbors of drug targets contribute to drug side-effect similarityLarge-scale elucidation of drug response pathways in humansTranscriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKIIConnectivity Mapping for Candidate Therapeutics Identification Using Next Generation Sequencing RNA-Seq DataIntegrated analysis of drug-induced gene expression profiles predicts novel hERG inhibitorsPrediction of drug-target interactions for drug repositioning only based on genomic expression similarityTowards structural systems pharmacology to study complex diseases and personalized medicineA Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning PredictionsGene-Set Local Hierarchical Clustering (GSLHC)--A Gene Set-Based Approach for Characterizing Bioactive Compounds in Terms of Biological Functional GroupsA Novel Drug-Mouse Phenotypic Similarity Method Detects Molecular Determinants of Drug EffectsA survey of current trends in computational drug repositioningA Systematic Framework for Drug Repositioning from Integrated Omics and Drug Phenotype Profiles Using Pathway-Drug NetworkElucidating the modes of action for bioactive compounds in a cell-specific manner by large-scale chemically-induced transcriptomicsInferring gene targets of drugs and chemical compounds from gene expression profilesSTITCH 3: zooming in on protein-chemical interactionsTranscriptional data: a new gateway to drug repositioning?Finding the targets of a drug by integration of gene expression data with a protein interaction network.Drug repositioning: a machine-learning approach through data integration.Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis.Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis.Predicting target proteins for drug candidate compounds based on drug-induced gene expression data in a chemical structure-independent manner.Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugsThe effect of network biology on drug toxicology.Systematic evaluation of connectivity map for disease indicationsCellFateScout - a bioinformatics tool for elucidating small molecule signaling pathways that drive cells in a specific directionNetwork based elucidation of drug response: from modulators to targets.Probabilistic drug connectivity mapping.Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layersA Molecular-Level Landscape of Diet-Gut Microbiome Interactions: Toward Dietary Interventions Targeting Bacterial GenesAn integrative analysis of small molecule transcriptional responses in the human malaria parasite Plasmodium falciparumA gene-signature progression approach to identifying candidate small-molecule cancer therapeutics with connectivity mappingInferring Infection Patterns Based on a Connectivity Map of Host Transcriptional Responses.A review of connectivity map and computational approaches in pharmacogenomics.FacPad: Bayesian sparse factor modeling for the inference of pathways responsive to drug treatment.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Drug-induced regulation of target expression
@ast
Drug-induced regulation of target expression
@en
Drug-induced regulation of target expression
@nl
type
label
Drug-induced regulation of target expression
@ast
Drug-induced regulation of target expression
@en
Drug-induced regulation of target expression
@nl
altLabel
Drug-Induced Regulation of Target Expression
@en
prefLabel
Drug-induced regulation of target expression
@ast
Drug-induced regulation of target expression
@en
Drug-induced regulation of target expression
@nl
P2860
P50
P3181
P1476
Drug-induced regulation of target expression
@en
P2093
Michael Kuhn
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.1000925
P407
P577
2010-09-09T00:00:00Z