about
Genome-scale screening of drug-target associations relevant to Ki using a chemogenomics approachCharting the molecular network of the drug target Bcr-AblData-driven prediction of drug effects and interactionsPredicting new molecular targets for known drugsValidating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortalityDrug Repurposing Is a New Opportunity for Developing Drugs against Neuropsychiatric DisordersSystems Pharmacology in Small Molecular Drug DiscoveryBiomarker-based drug safety assessment in the age of systems pharmacology: from foundational to regulatory scienceSystematic analysis of the associations between adverse drug reactions and pathwaysNetwork-based approaches in drug discovery and early developmentStrategic applications of gene expression: from drug discovery/development to bedsideTranslational bioinformatics: linking the molecular world to the clinical worldA survey on the computational approaches to identify drug targets in the postgenomic eraStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewThe emerging paradigm of network medicine in the study of human diseaseHarvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactomeMolecularly and clinically related drugs and diseases are enriched in phenotypically similar drug-disease pairsMolecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes DrugsApplications of systems approaches in the study of rheumatic diseases.ChemDes: an integrated web-based platform for molecular descriptor and fingerprint computationBioTriangle: a web-accessible platform for generating various molecular representations for chemicals, proteins, DNAs/RNAs and their interactionsLeveraging 3D chemical similarity, target and phenotypic data in the identification of drug-protein and drug-adverse effect associationsDASPfind: new efficient method to predict drug–target interactionsA fast topological analysis algorithm for large-scale similarity evaluations of ligands and binding pocketsDual- and triple-acting agents for treating core and co-morbid symptoms of major depression: novel concepts, new drugsIdentifying unexpected therapeutic targets via chemical-protein interactomeDeciphering diseases and biological targets for environmental chemicals using toxicogenomics networksNetwork-based relating pharmacological and genomic spaces for drug target identificationA structure-based approach for mapping adverse drug reactions to the perturbation of underlying biological pathwaysDrug-induced regulation of target expressionDrug discovery using chemical systems biology: identification of the protein-ligand binding network to explain the side effects of CETP inhibitorsLiterature mining for the discovery of hidden connections between drugs, genes and diseasesHuman disease-drug network based on genomic expression profilesThe Mycobacterium tuberculosis drugome and its polypharmacological implicationsA computational approach to analyze the mechanism of action of the kinase inhibitor bafetinibA computational approach to finding novel targets for existing drugsMining significant substructure pairs for interpreting polypharmacology in drug-target networkExploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case studyCombinations of protein-chemical complex structures reveal new targets for established drugsSystematic drug repositioning based on clinical side-effects
P2860
Q21133651-438FD35B-61F1-48EC-A08E-A8F621E02B76Q24317707-38DDE8A8-D7DE-4123-9325-8F5E214BDD6CQ24599300-11B03848-B28E-4FFD-B69F-4F3CB8647288Q24649687-C41CFD0F-ECF5-4F22-8FCE-CC4554683620Q24745996-11CE7353-7861-4280-A777-9B9A9D9C02B9Q26748728-8A2AB07C-0E42-4798-B350-A14276675B0DQ26768459-BF9EF0AC-DFB6-4698-8D24-25331DE7615BQ26778374-93D728A1-C146-41AE-8FF5-BFDEC45D8022Q26779991-A85BFAF8-AA34-4487-8104-9CE6C17F0711Q26827940-99649A92-6D1C-4FE1-B3C2-A8AC68048BB9Q26864172-5996FA42-CB70-47F3-9309-EECDF9967536Q27002440-5889EE05-5208-4955-B7A2-B9CB968BE9EFQ27003870-CE706D29-137A-4968-AAC0-D710D4E88C5EQ27008867-2002B7C0-4E37-4DE3-9632-91357781D1E2Q27026041-869127D2-8DE8-4C2E-848B-E08D6C77C8A3Q27335598-6DE69432-C736-4F55-B025-E9C7624FF1F4Q27499827-C39F852C-F0EC-4BF1-BA32-0FFAADC7E568Q27676922-C05C3C64-D0D9-4F30-AA78-FBFC264EBB35Q27692558-EE4A3A1F-3A7A-4450-821F-8C89115B65E7Q27902247-3FBF3C5C-9A2D-4516-A6C9-B9157EDBAE61Q27902315-9BFF5AAE-CE18-476E-82E9-1C4A2AFA3494Q27902320-D9131FF5-CB06-430D-AAFB-3581C446141DQ27902360-2CF804D6-5DFF-45F5-9D2C-679E0657B018Q27902362-D7C28A00-BE6A-45E0-93A4-382E8089EA31Q28305100-B0472810-A53A-4C27-A694-448723CBA90FQ28473107-4D977045-6273-448C-93EA-D2C9F1395B5CQ28473983-C86C2DEC-CD90-43F1-9A08-964387F60104Q28474912-808B2DD1-771D-4E0A-9BD6-3C84A6069BD3Q28475242-6B81BAEA-A67D-46CA-8DA5-0F6B6DE81503Q28475443-24E59008-EE37-4CD9-B802-CCCD202D7B58Q28475474-2755DC0C-49DD-4EBB-B9F4-DFCDDD299C8EQ28475561-BF2B165B-ACC4-4BE2-AAD9-5C78E1E8FDFAQ28475892-6CAA4387-C55E-44DF-BB85-AB36E8CD6143Q28476004-BF7AD546-EC74-4B65-9548-EF1C6D923E53Q28476189-E4734590-8C56-47F1-AACD-E5F85935CC41Q28476770-E618A28A-41D8-4F7E-BCB8-C179470B45F5Q28477249-4B479F56-2A5B-44F6-B5BC-C3A8ABD68277Q28477582-F77B9665-84BA-49A0-B77A-F73BDFC4E351Q28478053-A47BA0FD-D082-4393-B195-7E8A700E3AB6Q28478506-8B37F16C-B5E8-44A1-9DD3-A64D5D8EBB4C
P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Drug target identification using side-effect similarity
@ast
Drug target identification using side-effect similarity
@en
type
label
Drug target identification using side-effect similarity
@ast
Drug target identification using side-effect similarity
@en
altLabel
Drug Target Identification Using Side-Effect Similarity
@en
prefLabel
Drug target identification using side-effect similarity
@ast
Drug target identification using side-effect similarity
@en
P2860
P50
P3181
P356
P1433
P1476
Drug target identification using side-effect similarity
@en
P2093
Michael Kuhn
P2860
P304
P3181
P356
10.1126/SCIENCE.1158140
P407
P577
2008-07-01T00:00:00Z