Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer - Wikidata - wikimedia - TriplyDB

Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer

Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer

http://www.wikidata.org/entity/Q28477384

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Curcumin AntiCancer Studies in Pancreatic Cancer Cancer of the Pancreas: Molecular Pathways and Current Advancement in Treatment The Role of microRNAs in the Diagnosis and Treatment of Pancreatic Adenocarcinoma Cancer Stem Cells: The Potential Targets of Chinese Medicines and Their Active Compounds MicroRNA Targeted Therapeutic Approach for Pancreatic Cancer The critical roles of miR-21 in anti-cancer effects of curcumin Targeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacy Phytochemicals modulate carcinogenic signaling pathways in breast and hormone-related cancers Perspectives on new synthetic curcumin analogs and their potential anticancer properties Pancreatic cancer stem cells: emerging target for designing novel therapy The role of cancer stem cells and miRNAs in defining the complexities of brain metastasis Targeting CSC-related miRNAs for cancer therapy by natural agents The miR-200 and miR-221/222 microRNA families: opposing effects on epithelial identity MicroRNAs as targets for dietary and pharmacological inhibitors of mutagenesis and carcinogenesis Clinical advances in molecular biomarkers for cancer diagnosis and therapy Concise Review: Stem Cells in Pancreatic Cancer: From Concept to Translation Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment 3, 3'-Diindolylmethane enhances the effectiveness of herceptin against HER-2/neu-expressing breast cancer cells Prostate cancer stem cell-targeted efficacy of a new-generation taxoid, SBT-1214 and novel polyenolic zinc-binding curcuminoid, CMC2.24 Difluorinated-curcumin (CDF) restores PTEN expression in colon cancer cells by down-regulating miR-21 Curcumin intake affects miRNA signature in murine melanoma with mmu-miR-205-5p most significantly altered MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells.Sweating the small stuff: microRNAs and genetic changes define pancreatic cancer.Deregulation of miR-146a expression in a mouse model of pancreatic cancer affecting EGFR signaling.Curcumin: a potential candidate in prevention of cancer via modulation of molecular pathways.microRNA expression profile in a large series of bladder tumors: identification of a 3-miRNA signature associated with aggressiveness of muscle-invasive bladder cancer.Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN Hypoxia induced aggressiveness of prostate cancer cells is linked with deregulated expression of VEGF, IL-6 and miRNAs that are attenuated by CDF.Network modeling of CDF treated pancreatic cancer cells reveals a novel c-myc-p73 dependent apoptotic mechanism.Genetic and molecular alterations in pancreatic cancer: implications for personalized medicine.The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome.Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells miR-150-5p inhibits hepatoma cell migration and invasion by targeting MMP14.MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell.Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy.MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.Inflammaging and cancer: a challenge for the Mediterranean diet Manipulating miRNA Expression: A Novel Approach for Colon Cancer Prevention and Chemotherapy Pancreatic cancer tumour initiating cells: the molecular regulation and therapeutic values Inactivation of Ink4a/Arf leads to deregulated expression of miRNAs in K-Ras transgenic mouse model of pancreatic cancer.

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Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer

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Amro Aboukameel

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Bin Bao

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Dejuan Kong

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Philip A Philip

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Sanila H Sarkar

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Shadan Ali

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Subhash Padhye

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Zhiwei Wang

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P2860

Mammary stem cells, self-renewal pathways, and carcinogenesis

Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF

Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells

NF-kappaB, inflammation and pancreatic carcinogenesis: NF-kappaB as a chemoprevention target (review)

MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

miR-146a suppresses invasion of pancreatic cancer cells

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

Cancer statistics, 2009

MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival

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