about
Computational design of a PDZ domain peptide inhibitor that rescues CFTR activityPrinciples and Overview of Sampling Methods for Modeling Macromolecular Structure and DynamicsComputational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone TemplateStructure-guided deimmunization of therapeutic proteinsAmino-acid site variability among natural and designed proteinsProtein side-chain modeling with a protein-dependent optimized rotamer library.Computational approaches for rational design of proteins with novel functionalitiesProtein deimmunization via structure-based design enables efficient epitope deletion at high mutational loadsAntibody humanization by structure-based computational protein design.comets (Constrained Optimization of Multistate Energies by Tree Search): A Provable and Efficient Protein Design Algorithm to Optimize Binding Affinity and Specificity with Respect to Sequence.LUTE (Local Unpruned Tuple Expansion): Accurate Continuously Flexible Protein Design with General Energy Functions and Rigid Rotamer-Like Efficiency.Multistate Computational Protein Design with Backbone Ensembles.Parallel Computational Protein Design.Dead-end elimination with perturbations (DEEPer): a provable protein design algorithm with continuous sidechain and backbone flexibility.Structure and dynamics of an imidazoline nitroxide side chain with strongly hindered internal motion in proteins.An efficient parallel algorithm for accelerating computational protein design.An energy-based conformer library for side chain optimization: improved prediction and adjustable sampling.OSPREY: protein design with ensembles, flexibility, and provable algorithms.Computational design of protein-small molecule interfaces.Protein design algorithms predict viable resistance to an experimental antifolateMolprobity's ultimate rotamer-library distributions for model validationEpiSweep: Computationally Driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity While Maintaining Function.A critical analysis of computational protein design with sparse residue interaction graphs.BWM*: A Novel, Provable, Ensemble-based Dynamic Programming Algorithm for Sparse Approximations of Computational Protein Design.Energy functions in de novo protein design: current challenges and future prospects.Predicting self-assembly: from empirism to determinism.OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design.Algorithms for protein design.Deterministic Search Methods for Computational Protein Design.Improving the accuracy of protein stability predictions with multistate design using a variety of backbone ensembles.Fast search algorithms for computational protein design.Computationally driven antibody engineering enables simultaneous humanization and thermostabilization.Improved energy bound accuracy enhances the efficiency of continuous protein design.Compact Representation of Continuous Energy Surfaces for More Efficient Protein Design.Optimization of rotamers prior to template minimization improves stability predictions made by computational protein design.Fast gap-free enumeration of conformations and sequences for protein design.CATS (Coordinates of Atoms by Taylor Series): protein design with backbone flexibility in all locally feasible directions.Computationally-driven identification of antibody epitopes.Methods for the Development of In Silico GPCR Models.Recent advances in automated protein design and its future challenges.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Protein design using continuous rotamers
@ast
Protein design using continuous rotamers
@en
Protein design using continuous rotamers
@nl
type
label
Protein design using continuous rotamers
@ast
Protein design using continuous rotamers
@en
Protein design using continuous rotamers
@nl
prefLabel
Protein design using continuous rotamers
@ast
Protein design using continuous rotamers
@en
Protein design using continuous rotamers
@nl
P2860
P1476
Protein design using continuous rotamers
@en
P2093
Bruce R Donald
Kyle E Roberts
P2860
P304
P356
10.1371/JOURNAL.PCBI.1002335
P407
P50
P577
2012-01-01T00:00:00Z