Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose
about
The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129Formation of dTDP-rhamnose is essential for growth of mycobacteriaThe genome of Mycobacterium leprae: a minimal mycobacterial gene set.Bacterial glycobiology: rhamnose-containing cell wall polysaccharides in Gram-positive bacteriaInhibition of Mycobacterium-RmlA by Molecular Modeling, Dynamics Simulation, and Docking.UDP-glucose 4, 6-dehydratase activity plays an important role in maintaining cell wall integrity and virulence of Candida albicansComparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidatesA dual read-out assay to evaluate the potency of compounds active against Mycobacterium tuberculosisIdentification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-d-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC)RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformationHigh-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.Rv3634c from Mycobacterium tuberculosis H37Rv encodes an enzyme with UDP-Gal/Glc and UDP-GalNAc 4-epimerase activitiesNew small-molecule synthetic antimycobacterials.Cyclic di-GMP regulates Mycobacterium tuberculosis resistance to ethionamideChemical structure of Trichomonas vaginalis surface lipoglycan: a role for short galactose (β1-4/3) N-acetylglucosamine repeats in host cell interactionLipoglycans contribute to innate immune detection of mycobacteriaTrichomonas vaginalis lipophosphoglycan mutants have reduced adherence and cytotoxicity to human ectocervical cellsSuppressive subtractive hybridization detects extensive genomic diversity in Thermotoga maritima.Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis.The cell envelope glycoconjugates of Mycobacterium tuberculosisElucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction.Current status and future development of antitubercular chemotherapy.A recombinant horseshoe crab plasma lectin recognizes specific pathogen-associated molecular patterns of bacteria through rhamnose.Antimicrobial activity and cytotoxicity of some 2-amino-5-alkylidene-thiazol-4-ones.Bacterial cell-envelope glycoconjugates.Novel inhibitors of Mycobacterium tuberculosis dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) identified by virtual screening.Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interactionRecent advances towards identification of new drug targets for Mycobacterium tuberculosis.Comparative cell wall core biosynthesis in the mycolated pathogens, Mycobacterium tuberculosis and Corynebacterium diphtheriae.Defining mycobacteria: Shared and specific genome features for different lifestylesTargeting the formation of the cell wall core of M. tuberculosis.Proteome analyses of heme-dependent respiration in Lactococcus lactis: involvement of the proteolytic system.Effects of histidine protonation and rotameric states on virtual screening of M. tuberculosis RmlC.Non-carbohydrate inhibitors of the lectin DC-SIGN.S-layer nanoglycobiology of bacteria.Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis.Recent advances in antituberculous drug development and novel drug targets.Protein targets for structure-based anti-Mycobacterium tuberculosis drug discovery.The Production and Utilization of GDP-glucose in the Biosynthesis of Trehalose 6-Phosphate by Streptomyces venezuelae.The Mycobacterial Cell Wall--Peptidoglycan and Arabinogalactan.
P2860
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P2860
Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose
description
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Mai 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/05/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/05/01)
@nl
наукова стаття, опублікована в травні 2001
@uk
مقالة علمية (نشرت في مايو 2001)
@ar
name
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@ast
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@en
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@nl
type
label
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@ast
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@en
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@nl
prefLabel
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@ast
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@en
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@nl
P2093
P2860
P921
P1476
Drug targeting Mycobacterium t ...... dTDP-glucose to dTDP-rhamnose
@en
P2093
M. R. McNeil
M. S. Scherman
R. J. Stern
S. G. Franzblau
V. C. Jones
V. D. Vissa
W. H. Lewis
P2860
P304
P356
10.1128/AAC.45.5.1407-1416.2001
P407
P577
2001-05-01T00:00:00Z