High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv. - Wikidata - wikimedia - TriplyDB

High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

http://www.wikidata.org/entity/Q33503956

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Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis Learning from the past for TB drug discovery in the future New target prediction and visualization tools incorporating open source molecular fingerprints for TB Mobile 2.0 Potential inhibitors for isocitrate lyase of Mycobacterium tuberculosis and non-M. tuberculosis: a summary Filtration improves the performance of a high-throughput screen for anti-mycobacterial compounds 8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications A high-throughput screen identifies a new natural product with broad-spectrum antibacterial activity Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB A dual read-out assay to evaluate the potency of compounds active against Mycobacterium tuberculosis Enhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian models Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis Looking back to the future: predicting in vivo efficacy of small molecules versus Mycobacterium tuberculosis Interaction of ATP with a small heat shock protein from Mycobacterium leprae: effect on its structure and function Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepacia Identification of New Molecular Entities (NMEs) as Potential Leads against Tuberculosis from Open Source Compound Repository Screening and Development of New Inhibitors of FtsZ from M. Tuberculosis Open Source Bayesian Models. 1. Application to ADME/Tox and Drug Discovery Datasets Bigger data, collaborative tools and the future of predictive drug discovery TB Mobile: a mobile app for anti-tuberculosis molecules with known targets Combining cheminformatics methods and pathway analysis to identify molecules with whole-cell activity against Mycobacterium tuberculosis Adapting high-throughput screening methods and assays for biocontainment laboratories.Computational models for in-vitro anti-tubercular activity of molecules based on high-throughput chemical biology screening datasets.MycPermCheck: the Mycobacterium tuberculosis permeability prediction tool for small molecules.Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32 Fusing dual-event data sets for Mycobacterium tuberculosis machine learning models and their evaluation.Are bigger data sets better for machine learning? Fusing single-point and dual-event dose response data for Mycobacterium tuberculosis Predictive models for anti-tubercular molecules using machine learning on high-throughput biological screening datasets.Machine Learning Model Analysis and Data Visualization with Small Molecules Tested in a Mouse Model of Mycobacterium tuberculosis Infection (2014-2015).Discovery and validation of new antitubercular compounds as potential drug leads and probes.Antituberculosis activity of the molecular libraries screening center network library.Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosis.The DNA relaxation activity and covalent complex accumulation of Mycobacterium tuberculosis topoisomerase I can be assayed in Escherichia coli: application for identification of potential FRET-dye labeling sites.Validating new tuberculosis computational models with public whole cell screening aerobic activity datasets.High throughput screening of a library based on kinase inhibitor scaffolds against Mycobacterium tuberculosis H37Rv.The structure-activity relationship of urea derivatives as anti-tuberculosis agents.Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery.Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis.Parallel solution-phase synthesis of an adenosine antibiotic analog library.Identification of a chemical that inhibits the mycobacterial UvrABC complex in nucleotide excision repair

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High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

http://www.wikidata.org/entity/Q33503956

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

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High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

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High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

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High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

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High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

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High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

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J.TUBE.2009.05.008

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High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

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Alka Mehta

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Barbara E Laughon

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Cecil D Kwong

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Dustin N Showe

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E Lucile White

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Ellen R Faaleolea

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John A Secrist

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Joseph A Maddry

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Judith V Hobrath

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Lynn Rasmussen

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P2860

Hydroxyquinolines inhibit ribonucleic acid-dependent deoxyribonucleic acid polymerase and inactivate Rous sarcoma virus and herpes simplex virus

Extensively drug-resistant tuberculosis, Italy and Germany

Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis

Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa

8-Hydroxyquinolines with the potential for long-term anticaries activity: design, synthesis, and in vitro evaluation

Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis

Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs

Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium

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10.1016/J.TUBE.2009.05.008

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5

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Mycobacterium tuberculosis

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