Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
about
Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblastsNek10 mediates G2/M cell cycle arrest and MEK autoactivation in response to UV irradiationNek1 regulates cell death and mitochondrial membrane permeability through phosphorylation of VDAC1Nek1 and TAZ interact to maintain normal levels of polycystin 2Involvement of GLTSCR2 in the DNA Damage Response.Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members.Role of senescence and mitotic catastrophe in cancer therapy."Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinasesPhosphorylation by Nek1 regulates opening and closing of voltage dependent anion channel 1.Inducible response required for repair of low-dose radiation damage in human fibroblasts.Increased Nek1 expression in renal cell carcinoma cells is associated with decreased sensitivity to DNA-damaging treatmentA gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress responseMutation of NIMA-related kinase 1 (NEK1) leads to chromosome instabilityNek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATRExpression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney diseaseThe NEK1 interactor, C21ORF2, is required for efficient DNA damage repair.NEK8 regulates DNA damage-induced RAD51 foci formation and replication fork protectionNek1 kinase associates with ATR-ATRIP and primes ATR for efficient DNA damage signaling.Nek1 phosphorylates Von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization.Insights into dynamic mitotic chromatin organization through the NIMA kinase suppressor SonC, a chromatin-associated protein involved in the DNA damage response.Analysis of chromosomal aberration (1, 3, and 8) and association of microRNAs in uveal melanoma.Beyond ATM: the protein kinase landscape of the DNA damage response.Cell cycle regulation by the NEK family of protein kinases.Nek family of kinases in cell cycle, checkpoint control and cancer.Nek1 silencing slows down DNA repair and blocks DNA damage-induced cell cycle arrest.Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis.Nek1 Regulates Rad54 to Orchestrate Homologous Recombination and Replication Fork Stability.DYNLL/LC8 protein controls signal transduction through the Nek9/Nek6 signaling module by regulating Nek6 binding to Nek9.p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells.Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity.High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer.Actin organization and endocytic trafficking are controlled by a network linking NIMA-related kinases to the CDC-42-SID-3/ACK1 pathway.Kinase inhibitor profile for human nek1, nek6, and nek7 and analysis of the structural basis for inhibitor specificity.
P2860
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P2860
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
description
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Oktober 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/10/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/10/01)
@nl
наукова стаття, опублікована в жовтні 2008
@uk
مقالة علمية (نشرت في أكتوبر 2008)
@ar
name
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@ast
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@en
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@nl
type
label
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@ast
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@en
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@nl
prefLabel
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@ast
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@en
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@nl
P2093
P2860
P356
P1433
P1476
Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control
@en
P2093
Chi-Fen Chen
Daniel J. Riley
Phang-Lang Chen
Xianzhi Jiang
Yumay Chen
P2860
P304
P356
10.4161/CC.7.20.6815
P577
2008-10-01T00:00:00Z