Syk, activated by cross-linking the B-cell antigen receptor, localizes to the cytosol where it interacts with and phosphorylates alpha-tubulin on tyrosine
about
The Syk tyrosine kinase suppresses malignant growth of human breast cancer cellsThe protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinaseThe protein-tyrosine kinase Syk interacts with TRAF-interacting protein TRIP in breast epithelial cellsFunctional roles of Syk in macrophage-mediated inflammatory responsesThe Syk kinase SmTK4 of Schistosoma mansoni is involved in the regulation of spermatogenesis and oogenesisInhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.Syk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130Protein tyrosine kinase p53/p56(lyn) forms complexes with gamma-tubulin in rat basophilic leukemia cellsReal-time cross-correlation image analysis of early events in IgE receptor signalingDAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinasePosttranslational modification of tubulin by palmitoylation: I. In vivo and cell-free studiesTOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells.Exposure of beta-tubulin regions defined by antibodies on an Arabidopsis thaliana microtubule protofilament model and in the cellsUbiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement.The tubulin code: molecular components, readout mechanisms, and functionsCalling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer.PKIS: computational identification of protein kinases for experimentally discovered protein phosphorylation sitesNanomechanical property maps of breast cancer cells as determined by multiharmonic atomic force microscopy reveal Syk-dependent changes in microtubule stability mediated by MAP1B.Writing and Reading the Tubulin Code.Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates.Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinaseCytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanismT cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk.The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1.ER-27319, an acridone-related compound, inhibits release of antigen-induced allergic mediators from mast cells by selective inhibition of fcepsilon receptor I-mediated activation of SykTyr130 phosphorylation triggers Syk release from antigen receptor by long-distance conformational uncoupling.The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigensIdentification of direct tyrosine kinase substrates based on protein kinase assay-linked phosphoproteomicsSyk and pTyr'd: Signaling through the B cell antigen receptorPiceatannol, a derivative of resveratrol, moderately slows I(Na) inactivation and exerts antiarrhythmic action in ischaemia-reperfused rat hearts.Role of the protein tyrosine kinase Syk in regulating cell-cell adhesion and motility in breast cancer cells.Cytoskeleton in mast cell signaling.Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell-cell adhesion.TEL-Syk fusion constitutively activates PI3-K/Akt, MAPK and JAK2-independent STAT5 signal pathways.A comprehensive characterization of the T-cell antigen receptor complex composition by microcapillary liquid chromatography-tandem mass spectrometry.Disruption of microtubules in living cells by tyrphostin AG-1714.Phosphorylation- and activation-independent association of the tyrosine kinase Syk and the tyrosine kinase substrates Cbl and Vav with tubulin in B-cells.Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains.
P2860
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P2860
Syk, activated by cross-linking the B-cell antigen receptor, localizes to the cytosol where it interacts with and phosphorylates alpha-tubulin on tyrosine
description
1996 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1996
@ast
im März 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/03/01)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/03/01)
@nl
наукова стаття, опублікована в березні 1996
@uk
name
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@ast
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@en
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@nl
type
label
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@ast
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@en
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@nl
prefLabel
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@ast
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@en
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@nl
P2093
P356
P1476
Syk, activated by cross-linkin ...... ates alpha-tubulin on tyrosine
@en
P2093
D. J. Asai
J. D. Peters
M. L. Harrison
M. T. Furlong
R. L. Geahlen
P304
P356
10.1074/JBC.271.9.4755
P407
P577
1996-03-01T00:00:00Z