RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts
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NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomasRaf family kinases: old dogs have learned new tricksInsulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.Mechanism of the spatio-temporal regulation of Ras and Rap1.The strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPasesThe heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytesIdentification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap125I-4-(2-[7-amino-2-[2-furyl][1,2,4]triazolo[2,3-a][1,3,5] triazin-5-yl-amino]ethyl)phenol, a high affinity antagonist radioligand selective for the A2a adenosine receptorRap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functionsIncreased expression of the Ras suppressor Rsu-1 enhances Erk-2 activation and inhibits Jun kinase activationIdentification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3GThe M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytesMultiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functionsFyn and Lck tyrosine kinases regulate tyrosine phosphorylation of p105CasL, a member of the p130Cas docking protein family, in T-cell receptor-mediated signallingRequirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesisAdaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells.Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.Topological analysis of MAPK cascade for kinetic ErbB signaling.Drosophila Raf's N terminus contains a novel conserved region and can contribute to torso RTK signaling.Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase.The Rap1 GTPase functions as a regulator of morphogenesis in vivo.CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function.Rap2 as a slowly responding molecular switch in the Rap1 signaling cascade.Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathwaysOn the mitogenic properties of Rap1b: cAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b.Dynamics of the G protein-coupled vasopressin V2 receptor signaling network revealed by quantitative phosphoproteomics.Human papillomavirus type 16 E6 amino acid 83 variants enhance E6-mediated MAPK signaling and differentially regulate tumorigenesis by notch signaling and oncogenic Ras.Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway.Small G protein signaling in neuronal plasticity and memory formation: the specific role of ras family proteinsDifferential effects on cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo.Flow-mediated endothelial mechanotransduction.PKA and Epac synergistically inhibit smooth muscle cell proliferation.ERK crosstalks with 4EBP1 to activate cyclin D1 translation during quinol-thioether-induced tuberous sclerosis renal cell carcinoma.Constitutively active signaling by the G protein βγ-subunit mediates intrinsically increased phosphodiesterase-4 activity in human asthmatic airway smooth muscle cells.Expression of the TSC2 product tuberin and its target Rap1 in normal human tissuesThe role of the small GTPase Rap in Drosophila R7 photoreceptor specification.Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptorAntigen-driven T cell anergy and defective memory T cell response via deregulated Rap1 activation in SPA-1-deficient mice.
P2860
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P2860
RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts
description
1993 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1993
@ast
im September 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/09/01)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/09/01)
@nl
наукова стаття, опублікована у вересні 1993
@uk
مقالة علمية (نشرت في سبتمبر 1993)
@ar
name
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@ast
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@en
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@nl
type
label
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@ast
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@en
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@nl
prefLabel
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@ast
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@en
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@nl
P2093
P2860
P1433
P1476
RapV12 antagonizes Ras-depende ...... A and EGF in Rat-1 fibroblasts
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1993.TB06022.X
P407
P577
1993-09-01T00:00:00Z