Suppressor of fused links fused and Cubitus interruptus on the hedgehog signalling pathway
about
GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localizationMammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathwayStructural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/CiThe negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteinsSuppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complexSuppressor of fused regulates Gli activity through a dual binding mechanismHedgehog signal transduction proteins: contacts of the Fused kinase and Ci transcription factor with the kinesin-related protein Costal2.Aberrant activation of the hedgehog signaling pathway in malignant hematological neoplasmsDecoding the phosphorylation code in Hedgehog signal transductionCharacterization of the physical interaction of Gli proteins with SUFU proteinsSuppressor of fused negatively regulates beta-catenin signalingIdentification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2.Extensive phosphorylation of Smoothened in Hedgehog pathway activationActivation of Erk by sonic hedgehog independent of canonical hedgehog signalling.Hedgehog signaling downregulates suppressor of fused through the HIB/SPOP-Crn axis in Drosophila.Inhibition of the nuclear import of cubitus interruptus by roadkill in the presence of strong hedgehog signal.Mechanism and evolution of cytosolic Hedgehog signal transductionThe VACTERL association: lessons from the Sonic hedgehog pathway.The HIV-1 Vpu protein induces apoptosis in Drosophila via activation of JNK signalingRegulation of Hedgehog signaling: a complex story.Su(fu) switches Rdx functions to fine-tune hedgehog signaling in the Drosophila wing disk.The role of kinases in the Hedgehog signalling pathway.Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo.Multisite interaction with Sufu regulates Ci/Gli activity through distinct mechanisms in Hh signal transduction.A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog ResponseMyeloid leukemia factor is a conserved regulator of RUNX transcription factor activity involved in hematopoiesis.Regulation of Hedgehog signaling by ubiquitination.Extramacrochaetae imposes order on the Drosophila eye by refining the activity of the Hedgehog signaling gradientThe Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner.A quantification of pathway components supports a novel model of Hedgehog signal transductionSuppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapβ2 in Hedgehog signaling.An intramolecular association between two domains of the protein kinase Fused is necessary for Hedgehog signaling.The sonic hedgehog-GLI1 signaling pathway in brain tumor development.The Hedgehog signal transduction network.Decoding Ci: from partial degradation to inhibition.The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation.Mechanisms Regulating Protein Localization.Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors.Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus.
P2860
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P2860
Suppressor of fused links fused and Cubitus interruptus on the hedgehog signalling pathway
description
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Mai 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/05/07)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/05/07)
@nl
наукова стаття, опублікована в травні 1998
@uk
مقالة علمية (نشرت في 7-5-1998)
@ar
name
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@ast
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@en
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@nl
type
label
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@ast
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@en
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@nl
prefLabel
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@ast
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@en
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@nl
P2093
P1433
P1476
Suppressor of fused links fuse ...... he hedgehog signalling pathway
@en
P2093
A. Plessis
C. Lamour-Isnard
F. Dussillol
V. Monnier
P304
P356
10.1016/S0960-9822(98)70227-1
P407
P577
1998-05-07T00:00:00Z