Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA
about
The pharmacology of cyclic nucleotide-gated channels: emerging from the darknessAssembly of allosteric macromolecular switches: lessons from PKADesign principles underpinning the regulatory diversity of protein kinasesPKA controls calcium influx into motor neurons during a rhythmic behaviorThe Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal AdhesionsPKA Type II Holoenzyme Reveals a Combinatorial Strategy for Isoform DiversityMechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structureContribution of Non-catalytic Core Residues to Activity and Regulation in Protein Kinase AStructural insight into nucleotide recognition by human death-associated protein kinaseStructural basis for cAMP-mediated allosteric control of the catabolite activator protein.Mapping the structure and conformational movements of proteins with transition metal ion FRETNovel Isoform-Specific Interfaces Revealed by PKA RIIβ Holoenzyme StructuresStructure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA SignalingCyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor DesignCrystal Structure and Allosteric Activation of Protein Kinase C βIIRealizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα HoloenzymeCo-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide BindingCyclic AMP regulation of protein lysine acetylation in Mycobacterium tuberculosisLocalization and quaternary structure of the PKA RI holoenzymeA Conserved Glu–Arg Salt Bridge Connects Coevolved Motifs That Define the Eukaryotic Protein Kinase FoldStructure and Allostery of the PKA RII Tetrameric HoloenzymePKA RIα Homodimer Structure Reveals an Intermolecular Interface with Implications for Cooperative cAMP Binding and Carney Complex DiseaseThe central role of cAMP in regulating Plasmodium falciparum merozoite invasion of human erythrocytesDusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domainGrowth factor regulation of estrogen receptor coregulator PELP1 functions via Protein Kinase A pathwayEvolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunitsConservation, variability and the modeling of active protein kinasesIdentifying critical non-catalytic residues that modulate protein kinase A activityReversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMPDissociation between AKAP3 and PKARII promotes AKAP3 degradation in sperm capacitationAn electrostatic network and long-range regulation of Src kinasesDissecting the mechanism of Epac activation via hydrogen-deuterium exchange FT-IR and structural modeling.Signaling through dynamic linkers as revealed by PKAProtein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors.Double electron-electron resonance reveals cAMP-induced conformational change in HCN channels.Exploring the interaction between the protein kinase A catalytic subunit and caveolin-1 scaffolding domain with shotgun scanning, oligomer complementation, NMR, and dockingA generalized allosteric mechanism for cis-regulated cyclic nucleotide binding domains.Reciprocally coupled residues crucial for protein kinase Pak2 activity calculated by statistical coupling analysisSubstrate and docking interactions in serine/threonine protein kinasesp90 ribosomal S6 kinase 1 (RSK1) and the catalytic subunit of protein kinase A (PKA) compete for binding the pseudosubstrate region of PKAR1alpha: role in the regulation of PKA and RSK1 activities.
P2860
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P2860
Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA
description
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2005
@ast
im Februar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2005/02/04)
@nl
наукова стаття, опублікована в лютому 2005
@uk
مقالة علمية (نشرت في 4-2-2005)
@ar
name
Crystal structure of a complex ...... tory (RIalpha) subunits of PKA
@ast
Crystal structure of a complex ...... tory (RIalpha) subunits of PKA
@en
type
label
Crystal structure of a complex ...... tory (RIalpha) subunits of PKA
@ast
Crystal structure of a complex ...... tory (RIalpha) subunits of PKA
@en
prefLabel
Crystal structure of a complex ...... tory (RIalpha) subunits of PKA
@ast
Crystal structure of a complex ...... tory (RIalpha) subunits of PKA
@en
P2093
P3181
P356
P1433
P1476
Crystal structure of a complex ...... tory (RIalpha) subunits of PKA
@en
P2093
Nguyen-Huu Xuong
Susan S. Taylor
P304
P3181
P356
10.1126/SCIENCE.1104607
P407
P577
2005-02-04T00:00:00Z