A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases
about
RasGRP4 is a novel Ras activator isolated from acute myeloid leukemiaRapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cellsThe RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membraneEpithelial-mesenchymal transition and its implications for fibrosisThe tumor suppressor PP2A Abeta regulates the RalA GTPaseCatalytic competence of the Ras-GEF domain of hSos1 requires intra-REM domain interactions mediated by phenylalanine 577Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascadesA vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol estersActivation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factorsRap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functionsEffect of neurofibromatosis type I mutations on a novel pathway for adenylyl cyclase activation requiring neurofibromin and RasRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responsesMolecular mechanisms in uterine epithelium during trophoblast binding: the role of small GTPase RhoA in human uterine Ishikawa cells.The Dictyostelium genome encodes numerous RasGEFs with multiple biological rolesLte1 contributes to Bfa1 localization rather than stimulating nucleotide exchange by Tem1.Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanismsMycobacterium tuberculosis universal stress protein Rv2623 regulates bacillary growth by ATP-Binding: requirement for establishing chronic persistent infectionPhosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortexSrc-dependent TrkA transactivation is required for pituitary adenylate cyclase-activating polypeptide 38-mediated Rit activation and neuronal differentiationp75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cellsRap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activationDiacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signalingSignalling to actin: role of C3G, a multitasking guanine-nucleotide-exchange factor.C3G-mediated suppression of oncogene-induced focus formation in fibroblasts involves inhibition of ERK activation, cyclin A expression and alterations of anchorage-independent growth.Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.RalA but not RalB enhances polarized delivery of membrane proteins to the basolateral surface of epithelial cells.R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes.RalA activation at nascent lamellipodia of epidermal growth factor-stimulated Cos7 cells and migrating Madin-Darby canine kidney cells.Regulation of RasGRP1 function in T cell development and activation by its unique tail domain.The information highways of a biotechnological workhorse--signal transduction in Hypocrea jecorinaHuman RAS superfamily proteins and related GTPases.Noonan syndrome: clinical aspects and molecular pathogenesis.Gβγ subunits inhibit Epac-induced melanoma cell migration.Splice variants of SmgGDS control small GTPase prenylation and membrane localizationCARD9 mediates Dectin-1-induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity.Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors.Disorders of dysregulated signal traffic through the RAS-MAPK pathway: phenotypic spectrum and molecular mechanismsThe Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology.PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growthEpac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.
P2860
Q24292406-8D22687E-4BD7-4CBF-9CCD-9BD887EEF511Q24296811-62851DC4-6EC6-4AD8-9081-37B238EEF76CQ24297422-5FD07F70-BB40-4B05-ABF3-871AAAF37D67Q24302042-2246ABEF-1E76-4105-8A93-11E25FC4C4B0Q24307546-D4CB6CE6-1D1E-483C-A181-DF97EC7AC2DBQ24311972-0C4B46AE-CE96-4630-A1F7-CACACBC1371DQ24557569-0068B074-E00E-4CB8-A7FB-879109247141Q24559732-3C330202-ED7E-43CE-A335-E0676FB492BDQ24601002-F8B6C505-B4D4-4269-8040-5E6F520B668CQ24646480-6E5E5E28-327D-4A45-83DA-18F2430BC768Q24671862-C7B7E4F9-4B35-4137-A5E0-74E1890F3A30Q24681250-C3D4C600-8AF6-428F-9A08-9EAFEAC91AA5Q24795902-CBA4007E-5990-4CF3-AAEA-71AC0350170BQ24811271-AF207E90-B890-4748-8EC4-47F4CB0C9AACQ27940290-D4B6C710-54A4-47CB-809F-0FAFA33AC3B9Q28384212-B038AF3B-B14C-4906-B4B3-A1DFB6CE89AFQ28475519-5ED3D51B-FD23-4DC3-AB88-0F76C399959AQ28574924-E442618E-16C9-42D2-829F-B98F877FB125Q28583135-AFA0D951-3494-43B2-8B8C-50DE1779B302Q28583902-C909CEEE-85B7-47A0-8C3E-71EA9B2C749EQ28584307-A527365C-C668-42C9-AA34-27ED85824E04Q28588899-0C1689B9-33FC-4BC6-A20D-3ED0027A5A97Q30155824-0723871A-0AAD-431D-ACEF-1E1DE6AFDC27Q30164174-B8C308C9-070D-412F-BB85-09EFA70EC7F1Q30310839-FDE4C245-1DDA-4601-BE2A-9CBF22C3271FQ30449192-76AD776A-24A2-42CA-BFE0-E804BDCCFB49Q30479311-37A2F15A-059C-4756-927C-48E65AFA2290Q30593702-B84B4FA1-595D-4D1C-B75D-F3CE1AE5D765Q31067358-43C0CD5F-BCBE-4A42-A2F0-B4C8937E7B5DQ33370697-FA3A793F-5819-44B3-8183-52843A4DAD0CQ33689727-78833AE2-AE36-4FB0-B283-F8FF5B219192Q33806161-E27D1D61-B3AF-49FE-B31A-ECD7580E4A00Q33934632-7A96AFD9-4B31-411D-B3A9-4768645FFCB2Q34284968-4249A404-F8F7-4CB7-B3F9-485A70E68161Q34375193-5062B026-98E3-4D34-8FA1-886E88FCD8E8Q34411416-F8BA6306-A348-4B27-8BD6-6984B911AFB7Q34440570-C0A261CB-F80E-4328-96C9-09DAD64306A7Q34559555-5753469B-055D-4984-A6B1-75934AF8478FQ34658189-C076307B-9881-4769-A05A-612F26037AFBQ34667012-B09ABC4F-8F98-41B8-A1AC-15E4DE051116
P2860
A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases
description
2002 nî lūn-bûn
@nan
2002 թուականին հրատարակուած գիտական յօդուած
@hyw
2002 թվականին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A growing family of guanine nu ...... tivation of ras-family GTPases
@ast
A growing family of guanine nu ...... tivation of ras-family GTPases
@en
type
label
A growing family of guanine nu ...... tivation of ras-family GTPases
@ast
A growing family of guanine nu ...... tivation of ras-family GTPases
@en
prefLabel
A growing family of guanine nu ...... tivation of ras-family GTPases
@ast
A growing family of guanine nu ...... tivation of ras-family GTPases
@en
P3181
P1476
A growing family of guanine nu ...... tivation of Ras-family GTPases
@en
P2093
Ariel F Castro
Lawrence A Quilliam
P304
P3181
P356
10.1016/S0079-6603(02)71047-7
P50
P577
2002-01-01T00:00:00Z