The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
about
Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondriaGenetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation updateEndoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative diseaseATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell deathPINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motilityMUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkinLRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402Identification and characterization of unique proline-rich peptides binding to the mitochondrial fission protein hFis1Parkin is recruited selectively to impaired mitochondria and promotes their autophagyInner-membrane proteins PMI/TMEM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathwaysBroad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagyStructure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionNew insights into the role of mitochondria in aging: mitochondrial dynamics and moreMitochondria, calcium and cell death: a deadly triad in neurodegenerationActivation Mechanism of LRRK2 and Its Cellular Functions in Parkinson's DiseaseΑlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's DiseaseElectron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial BioenergeticsMitochondrial dynamism and heart disease: changing shape and shaping changeMouse models of Parkinson's disease associated with mitochondrial dysfunctionCell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative diseaseCalcium channel blockers and Alzheimer's diseaseMitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorderPathologic and therapeutic implications for the cell biology of parkinMitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infectionSelf and nonself: how autophagy targets mitochondria and bacteriaMitochondrial dysfunction and oxidative stress in Parkinson's diseaseNear-infrared 808 nm light boosts complex IV-dependent respiration and rescues a Parkinson-related pink1 modelMitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration.Mechanisms of mitophagyTissue- and cell-specific mitochondrial defect in Parkin-deficient miceThe yeast complex I equivalent NADH dehydrogenase rescues pink1 mutantsParkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.S-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegenerationMitochondria in the Aging Muscles of Flies and Mice: New Perspectives for Old CharactersMitochondrial Biology and Neurological DiseasesMolecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutantEvidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson diseaseDynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases
P2860
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P2860
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The Parkinson's disease genes ...... r inhibit fusion in Drosophila
@ast
The Parkinson's disease genes ...... r inhibit fusion in Drosophila
@en
type
label
The Parkinson's disease genes ...... r inhibit fusion in Drosophila
@ast
The Parkinson's disease genes ...... r inhibit fusion in Drosophila
@en
prefLabel
The Parkinson's disease genes ...... r inhibit fusion in Drosophila
@ast
The Parkinson's disease genes ...... r inhibit fusion in Drosophila
@en
P2093
P2860
P921
P3181
P356
P1476
The Parkinson's disease genes ...... r inhibit fusion in Drosophila
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.0803998105
P407
P577
2008-09-23T00:00:00Z