Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase
about
Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinaseAkt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targettingEvidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic functionInteraction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells.Akt phosphorylates and suppresses the transactivation of retinoic acid receptor alphaStructural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylationAkt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylationEphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with AktAnkrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2)AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosisPRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complexMOZ increases p53 acetylation and premature senescence through its complex formation with PMLAkt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREBActivity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioningC2 domain-containing phosphoprotein CDP138 regulates GLUT4 insertion into the plasma membrane.Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3Identification of filamin C as a new physiological substrate of PKBalpha using KESTRELWNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrateActivation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alphaThe PI3K-PDK1 connection: more than just a road to PKBRegulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2)Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusionIdentification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions.Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription.CARMA1 is required for Akt-mediated NF-kappaB activation in T cells.Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant miceThe ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase BTrypanosoma cruzi targets Akt in host cells as an intracellular antiapoptotic strategyAkt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptorThe TSC1-TSC2 complex: a molecular switchboard controlling cell growthAKT/PKB signaling: navigating downstreamRegulation of nuclear translocation of forkhead transcription factor AFX by protein kinase BBalancing Akt with S6K: implications for both metabolic diseases and tumorigenesisPhosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activityIdentification of Sin1 as an essential TORC2 component required for complex formation and kinase activity
P2860
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P2860
Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Molecular basis for the substr ...... KAP kinase-1 and p70 S6 kinase
@ast
Molecular basis for the substr ...... KAP kinase-1 and p70 S6 kinase
@en
type
label
Molecular basis for the substr ...... KAP kinase-1 and p70 S6 kinase
@ast
Molecular basis for the substr ...... KAP kinase-1 and p70 S6 kinase
@en
prefLabel
Molecular basis for the substr ...... KAP kinase-1 and p70 S6 kinase
@ast
Molecular basis for the substr ...... KAP kinase-1 and p70 S6 kinase
@en
P2093
P3181
P1433
P1476
Molecular basis for the substr ...... KAP kinase-1 and p70 S6 kinase
@en
P2093
B A Hemmings
F B Caudwell
M Andjelkovic
P304
P3181
P356
10.1016/S0014-5793(96)01370-1
P407
P577
1996-12-01T00:00:00Z