The linkage between protein folding and functional cooperativity: two sides of the same coin?
about
Evidence that membrane insertion of the cytosolic domain of Bcl-xL is governed by an electrostatic mechanismConsensus protein designStructural and energetic basis of allosteryThe ensemble nature of allosteryAllosteric communication occurs via networks of tertiary and quaternary motions in proteinsCoupling of receptor conformation and ligand orientation determine graded activityAllosteric Inhibition of a Zinc-Sensing Transcriptional Repressor: Insights into the Arsenic Repressor (ArsR) FamilyLigand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1Evolutionary information for specifying a protein foldEvolution-Based Functional Decomposition of ProteinsHot spots for allosteric regulation on protein surfacesStructural position correlation analysis (SPCA) for protein familyThe nature of protein domain evolution: shaping the interaction networkFrom Binding-Induced Dynamic Effects in SH3 Structures to Evolutionary Conserved SectorsTwo-state dynamics of the SH3-SH2 tandem of Abl kinase and the allosteric role of the N-capMultiple folding pathways of the SH3 domain.Structural cooperativity in the SH3 domain studied by site-directed mutagenesis and amide hydrogen exchange.Functionally and structurally relevant residues of enzymes: are they segregated or overlapping?Ligand binding analysis and screening by chemical denaturation shiftComputational modeling of allosteric regulation in the hsp90 chaperones: a statistical ensemble analysis of protein structure networks and allosteric communications.Tools to evaluate the conformation of protein products.Nonlinear elasticity, proteinquakes, and the energy landscapes of functional transitions in proteins.Src kinase conformational activation: thermodynamics, pathways, and mechanisms.Information theoretical quantification of cooperativity in signalling complexes.Structure-based predictive models for allosteric hot spots.The induction of folding cooperativity by ligand binding drives the allosteric response of tetracycline repressor.Troponin regulatory function and dynamics revealed by H/D exchange-mass spectrometry.Correlation analysis for protein evolutionary family based on amino acid position mutations and application in PDZ domain.Hydrophobic side chain dynamics of a glutamate receptor ligand binding domainLocal conformational fluctuations can modulate the coupling between proton binding and global structural transitions in proteins.Discovery of intramolecular signal transduction network based on a new protein dynamics model of energy dissipation.Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor bindingThermal stability of Cpl-7 endolysin from the streptococcus pneumoniae bacteriophage Cp-7; cell wall-targeting of its CW_7 motifs.Negative coupling as a mechanism for signal propagation between C2 domains of synaptotagmin I.Misrouted cell surface receptors as a novel disease aetiology and potential therapeutic target: the case of hypogonadotropic hypogonadism due to gonadotropin-releasing hormone resistance.Allosteric switching by mutually exclusive folding of protein domainsStructural dynamics, intrinsic disorder, and allostery in nuclear receptors as transcription factors.Guanylate kinase, induced fit, and the allosteric spring probe.Agonism/antagonism switching in allosteric ensembles.Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease.
P2860
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P2860
The linkage between protein folding and functional cooperativity: two sides of the same coin?
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The linkage between protein fo ...... y: two sides of the same coin?
@ast
The linkage between protein fo ...... y: two sides of the same coin?
@en
type
label
The linkage between protein fo ...... y: two sides of the same coin?
@ast
The linkage between protein fo ...... y: two sides of the same coin?
@en
prefLabel
The linkage between protein fo ...... y: two sides of the same coin?
@ast
The linkage between protein fo ...... y: two sides of the same coin?
@en
P1476
The linkage between protein fo ...... y: two sides of the same coin?
@en
P2093
Ernesto Freire
Stephanie A Leavitt
P304
P356
10.1146/ANNUREV.BIOPHYS.31.082901.134215
P50
P577
2001-10-25T00:00:00Z