pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk - Wikidata - wikimedia - TriplyDB

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

http://www.wikidata.org/entity/Q30452729

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Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activities Abl family kinases regulate endothelial barrier function in vitro and in mice Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes LIM domain-containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin-induced tyrosine phosphorylation of paxillin Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates The redistribution of cortactin into cell-matrix contact sites in human carcinoma cells with 11q13 amplification is associated with both overexpression and post-translational modification Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins Human immunodeficiency virus tat modulates the Flk-1/KDR receptor, mitogen-activated protein kinases, and components of focal adhesion in Kaposi's sarcoma cells.Regulation of focal adhesion kinase by a novel protein inhibitor FIP200 Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase.Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase Cross talk of pp125(FAK) and pp59(Lyn) non-receptor tyrosine kinases to insulin-mimetic signaling in adipocytes Focal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophy Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase.An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G Paxillin comes of age Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts Structural basis for the autoinhibition of focal adhesion kinase Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding.Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnover Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST

P2860

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P2860

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

http://www.wikidata.org/entity/Q30452729

description

1995 nî lūn-bûn

@nan

1995 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի մայիսին հրատարակված գիտական հոդված

@hy

1995年の論文

@ja

1995年論文

@yue

1995年論文

@zh-hant

1995年論文

@zh-hk

1995年論文

@zh-mo

1995年論文

@zh-tw

1995年论文

@wuu

name

pp125FAK-dependent tyrosine ph ...... -affinity binding site for Crk

@ast

pp125FAK-dependent tyrosine ph ...... -affinity binding site for Crk

@en

type

label

pp125FAK-dependent tyrosine ph ...... -affinity binding site for Crk

@ast

pp125FAK-dependent tyrosine ph ...... -affinity binding site for Crk

@en

prefLabel

pp125FAK-dependent tyrosine ph ...... -affinity binding site for Crk

@ast

pp125FAK-dependent tyrosine ph ...... -affinity binding site for Crk

@en

P1433

Q30452729-D2E3F6CC-7572-4ABA-AE56-3DDFDBE10117

P1476

Q30452729-B1AFEA17-CE92-4754-8684-4E23FEDE0BF3

P2093

Q30452729-9FBCC471-D30E-490B-88D7-C702D90A48C4

Q30452729-E1BD65BF-77F8-4394-98F2-04007A0F8EF5

P2860

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Q30452729-16FD1F5C-FCD9-4E07-ACC7-296F3022E5AB

P304

Q30452729-F35DBE9F-2CEA-486B-8FB4-0A6135783F40

P31

Q30452729-05DAC7BA-B28D-4F1D-9861-78E0DE427BA9

P356

Q30452729-52897559-539A-46A6-9CB0-BB57D8A0F815

P407

Q30452729-3E43FEA1-5A89-4C7E-BDC1-E15EA60E619A

P433

Q30452729-3082A773-1AA1-4802-9A5E-711BBE9F80D6

P478

Q30452729-79C93A72-26C0-4DB6-BACF-AFEFC9338714

P577

Q30452729-CE91F13E-5B10-489F-B27A-B90445376632

P5875

Q30452729-1FF125E1-5578-4737-828E-21445EC9C595

P698

Q30452729-D4AA0075-79FA-40C2-BFA2-79DB4BEC9E2B

P921

Q30452729-BF446FED-F878-4A46-89CF-B4BA9D4B1F7A

P932

Q30452729-7DF9D821-E1C8-4DAB-B0F2-1356678BF558

P356

P1433

Molecular and Cellular Biology

P1476

pp125FAK-dependent tyrosine ph ...... -affinity binding site for Crk

@en

P2093

J T Parsons

http://www.w3.org/2001/XMLSchema#string

M D Schaller

http://www.w3.org/2001/XMLSchema#string

P2860

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL

Isolation and chromosomal localization of CRKL, a human crk-like gene

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions.

P304

2635-2645

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/MCB.15.5.2635

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

15

http://www.w3.org/2001/XMLSchema#string

P577

1995-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

15660965

http://www.w3.org/2001/XMLSchema#string

P698

7537852

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

230493

http://www.w3.org/2001/XMLSchema#string