PICALM modulates autophagy activity and tau accumulation.
about
Genes associated with Alzheimer's disease: an overview and current statusThe iTRAPs: Guardians of Synaptic Vesicle Cargo Retrieval During EndocytosisTherapeutic targeting of autophagy in neurodegenerative and infectious diseasesAutophagosome dynamics in neurodegeneration at a glancePooled-matrix protein interaction screens using Barcode Fusion GeneticsAstrocyte calcium signaling: the third wave.Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity.Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits.A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction.TBC1D14 regulates autophagy via the TRAPP complex and ATG9 trafficMethods to analyze SNARE-dependent vesicular fusion events that regulate autophagosome biogenesis.Autophagic activity in neuronal cell deathStudying Autophagy in Zebrafish.Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology.Walking the tightrope: proteostasis and neurodegenerative disease.Evidence For and Against a Pathogenic Role of Reduced γ-Secretase Activity in Familial Alzheimer's Disease.Autophagy and Alzheimer's Disease.Mammalian autophagy and the plasma membrane.The road to restoring neural circuits for the treatment of Alzheimer's disease.Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?Prelysosomal Compartments in the Unconventional Secretion of Amyloidogenic Seeds.Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis.Autophagy in neurodegenerative diseases: pathogenesis and therapy.LRRK2 Promotes Tau Accumulation, Aggregation and Release.AD genetic risk factors and tau spreadingUnraveling the genes implicated in Alzheimer's disease.Relationships of circular RNA with diabetes and depression.Therapeutic implication of autophagy in neurodegenerative diseases.Partial loss of CALM function reduces Aβ42 production and amyloid deposition in vivo.What is the evidence that tau pathology spreads through prion-like propagation?Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis.β-Amyloid and the Pathomechanisms of Alzheimer's Disease: A Comprehensive View.Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease.The Interactive Effects of Age and PICALM rs541458 Polymorphism on Cognitive Performance, Brain Structure, and Function in Non-demented Elderly.The Role of Free Radicals in Autophagy Regulation: Implications for Ageing.PICALM rs3851179 Variant Confers Susceptibility to Alzheimer's Disease in Chinese Population.Using Drosophila Models of Amyloid Toxicity to Study Autophagy in the Pathogenesis of Alzheimer's Disease.Novel Modulators of Proteostasis: RNAi Screen of Chromosome I in a Heat Stress Paradigm in C. elegans.
P2860
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P2860
PICALM modulates autophagy activity and tau accumulation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
PICALM modulates autophagy activity and tau accumulation.
@ast
PICALM modulates autophagy activity and tau accumulation.
@en
type
label
PICALM modulates autophagy activity and tau accumulation.
@ast
PICALM modulates autophagy activity and tau accumulation.
@en
prefLabel
PICALM modulates autophagy activity and tau accumulation.
@ast
PICALM modulates autophagy activity and tau accumulation.
@en
P2093
P2860
P50
P356
P1476
PICALM modulates autophagy activity and tau accumulation.
@en
P2093
Ana Lopez Ramirez
Cahir J O'Kane
Catherine P Lavau
Claudia Puri
Daniel S Wechsler
David C Rubinsztein
Farah Siddiqi
Jacob L Mercer
Kevin Moreau
Maureen Betton
P2860
P2888
P356
10.1038/NCOMMS5998
P407
P577
2014-09-22T00:00:00Z
P5875
P6179
1036055287