Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection.
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Cellular adaptation contributes to calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeysCellular senescence and tumor suppressor gene p16Quality matters: how does mitochondrial network dynamics and quality control impact on mtDNA integrity?Somatic mutations in aging, cancer and neurodegenerationMitochondrial fragmentation in neurodegenerationMitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator miceActivation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver diseaseMitochondrial DNA deletion mutations and sarcopenia.Role of direct repeat and stem-loop motifs in mtDNA deletions: cause or coincidence?The role of mitochondrial DNA mutations in mammalian agingAccumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber lossAberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adultsCaloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscleGeneration and bioenergetic analysis of cybrids containing mitochondrial DNA from mouse skeletal muscle during aging.Age-related structural alterations in human skeletal muscle fibers and mitochondria are sex specific: relationship to single-fiber functionSomatic mitochondrial DNA deletions accumulate to high levels in aging human extraocular muscles.Differential regulation of the fiber type-specific gene expression of the sarcoplasmic reticulum calcium-ATPase isoforms induced by exercise training.Preventive effects of Chlorella on skeletal muscle atrophy in muscle-specific mitochondrial aldehyde dehydrogenase 2 activity-deficient mice.Laser capture microdissection of metachromatically stained skeletal muscle allows quantification of fiber type specific gene expression.Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damageMitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers.Evolution of the mitochondrial fusion-fission cycle and its role in agingRole of apoptosis in sarcopenia.Molecular mechanisms for age-associated mitochondrial deficiency in skeletal muscle.Selections that isolate recombinant mitochondrial genomes in animals.DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?Apoptosis and necrosis mediate skeletal muscle fiber loss in age-induced mitochondrial enzymatic abnormalities.The role of mitochondrial DNA mutations in aging and sarcopenia: implications for the mitochondrial vicious cycle theory of aging.Cerebral hypoxia and ischemia: the forensic point of view: a review.Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions.Fiber type-specific differences in glucose uptake by single fibers from skeletal muscles of 9- and 25-month-old rats.Molecular mechanisms of life- and health-span extension: role of calorie restriction and exercise intervention.Mitochondrial DNA deletion and sarcopenia.Molecular diagnostics and mitochondrial dysfunction: a future perspective.Mitochondrial quality control in insulin resistance and diabetes.Latent mitochondrial DNA deletion mutations drive muscle fiber loss at old age.Sarcopenia of aging: underlying cellular mechanisms and protection by calorie restriction.Mitochondrial death effectors: relevance to sarcopenia and disuse muscle atrophy.Cytochrome c oxidase deficiency in human posterior cricoarytenoid muscle.Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging.
P2860
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P2860
Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Mitochondrial DNA deletion mut ...... laser-capture microdissection.
@ast
Mitochondrial DNA deletion mut ...... laser-capture microdissection.
@en
type
label
Mitochondrial DNA deletion mut ...... laser-capture microdissection.
@ast
Mitochondrial DNA deletion mut ...... laser-capture microdissection.
@en
prefLabel
Mitochondrial DNA deletion mut ...... laser-capture microdissection.
@ast
Mitochondrial DNA deletion mut ...... laser-capture microdissection.
@en
P2093
P2860
P356
P1476
Mitochondrial DNA deletion mut ...... laser-capture microdissection.
@en
P2093
P2860
P304
P356
10.1093/NAR/29.21.4502
P407
P577
2001-11-01T00:00:00Z