Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.
about
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1Analysis of the Active-Site Mechanism of Tyrosyl-DNA Phosphodiesterase I: A Member of the Phospholipase D SuperfamilyIdentification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assayThe DNA binding and 3'-end preferential activity of human tyrosyl-DNA phosphodiesterase.Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages.Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B virusesEffects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1.Repair of topoisomerase I-mediated DNA damage.Tyrosyl-DNA phosphodiesterase as a target for anticancer therapyNovel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy
P2860
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P2860
Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.
@ast
Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.
@en
type
label
Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.
@ast
Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.
@en
prefLabel
Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.
@ast
Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.
@en
P2093
P2860
P356
P1476
Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.
@en
P2093
Alex B Burgin
Amy C Raymond
Marc C Rideout
P2860
P304
P356
10.1093/NAR/GKH796
P407
P577
2004-08-27T00:00:00Z