Characterization of phosphopeptide motifs specific for the Src homology 2 domains of signal transducer and activator of transcription 1 (STAT1) and STAT3.
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Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motifThe consequences of selective inhibition of signal transducer and activator of transcription 3 (STAT3) tyrosine705 phosphorylation by phosphopeptide mimetic prodrugs targeting the Src homology 2 (SH2) domainTargeting SH2 domains in breast cancerStructure of the SOCS4-ElonginB/C Complex Reveals a Distinct SOCS Box Interface and the Molecular Basis for SOCS-Dependent EGFR DegradationDefining the specificity space of the human SRC homology 2 domainCharacterization of the signaling capacities of the novel gp130-like cytokine receptorGenome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm.Structure-affinity relationships of glutamine mimics incorporated into phosphopeptides targeted to the SH2 domain of signal transducer and activator of transcription 3.A molecular model for the differential activation of STAT3 and STAT6 by the herpesviral oncoprotein tip.Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation.Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling.A novel Stat3 binding motif in Gab2 mediates transformation of primary hematopoietic cells by the Stk/Ron receptor tyrosine kinase in response to Friend virus infectionPotent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.Effects of the tumor microenvironment on the efficacy of tumor immunotherapy.Binding specificity of SH2 domains: insight from free energy simulations.Solid-phase synthesis of Stat3 inhibitors incorporating O-carbamoylserine and O-carbamoylthreonine as glutamine mimics.STAT3 Inhibition Induces Apoptosis in Cancer Cells Independent of STAT1 or STAT2.Introduction: History of SH2 Domains and Their Applications.Quantitative control of intracellular signaling activity through chimeric receptors incorporating multiple identical tyrosine motifs.Reconstitution of a cytokine receptor scaffold utilizing multiple different tyrosine motifs.Activation of target signal transducers utilizing chimeric receptors with signaling-molecule binding motifs.STAT3-stathmin interactions control microtubule dynamics in migrating T-cells.Pre-assembly of STAT4 with the human IFN-alpha/beta receptor-2 subunit is mediated by the STAT4 N-domain.Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor.
P2860
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P2860
Characterization of phosphopeptide motifs specific for the Src homology 2 domains of signal transducer and activator of transcription 1 (STAT1) and STAT3.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Characterization of phosphopep ...... scription 1 (STAT1) and STAT3.
@ast
Characterization of phosphopep ...... scription 1 (STAT1) and STAT3.
@en
type
label
Characterization of phosphopep ...... scription 1 (STAT1) and STAT3.
@ast
Characterization of phosphopep ...... scription 1 (STAT1) and STAT3.
@en
prefLabel
Characterization of phosphopep ...... scription 1 (STAT1) and STAT3.
@ast
Characterization of phosphopep ...... scription 1 (STAT1) and STAT3.
@en
P2093
P2860
P356
P1476
Characterization of phosphopep ...... scription 1 (STAT1) and STAT3.
@en
P2093
Elke Bieck
Fred Grossmüller
Johannes Ottl
Kurt Müller
Michèle Wiederkehr-Adam
Patrick Graff
Philipp Ernst
P2860
P304
16117-16128
P356
10.1074/JBC.M300261200
P407
P577
2003-02-18T00:00:00Z