Structure-affinity relationships of glutamine mimics incorporated into phosphopeptides targeted to the SH2 domain of signal transducer and activator of transcription 3.

Structure-affinity relationships of glutamine mimics incorporated into phosphopeptides targeted to the SH2 domain of signal transducer and activator of transcription 3.

Item
http://www.wikidata.org/entity/Q33811131
The consequences of selective inhibition of signal transducer and activator of transcription 3 (STAT3) tyrosine705 phosphorylation by phosphopeptide mimetic prodrugs targeting the Src homology 2 (SH2) domainTargeting SH2 domains in breast cancerA phosphopeptide mimetic prodrug targeting the SH2 domain of Stat3 inhibits tumor growth and angiogenesis.Binding modes of peptidomimetics designed to inhibit STAT3.Progress towards the development of SH2 domain inhibitors.Development of new N-Arylbenzamides as STAT3 Dimerization Inhibitors.Synthesis of triamino acid building blocks with different lipophilicitiesPotent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts.Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer AgentsFragment-based drug design and identification of HJC0123, a novel orally bioavailable STAT3 inhibitor for cancer therapy.Structure-Activity Studies of Phosphopeptidomimetic Prodrugs Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 3 (Stat3).Signal transducer and activator of transcription 3 (STAT3): a promising target for anticancer therapy.Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway.Design, synthesis, and in vitro characterization of novel hybrid peptidomimetic inhibitors of STAT3 proteinRank order entropy: why one metric is not enoughIdentification of Lead Compounds as Inhibitors of STAT3: Design, Synthesis and Bioactivity.
P2860

Structure-affinity relationships of glutamine mimics incorporated into phosphopeptides targeted to the SH2 domain of signal transducer and activator of transcription 3.

Item
http://www.wikidata.org/entity/Q33811131
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structure-affinity relationshi ...... activator of transcription 3.
@ast
Structure-affinity relationshi ...... activator of transcription 3.
@en
type
label
Structure-affinity relationshi ...... activator of transcription 3.
@ast
Structure-affinity relationshi ...... activator of transcription 3.
@en
prefLabel
Structure-affinity relationshi ...... activator of transcription 3.
@ast
Structure-affinity relationshi ...... activator of transcription 3.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Structure-affinity relationshi ...... activator of transcription 3.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932