The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations
about
Structural basis for functional tetramerization of lentiviral integraseThe three-dimensional structure of a Tn5 transposase-related protein determined to 2.9-A resolutionStructure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein.Functional and structural characterization of the integrase from the prototype foamy virusCrystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding siteStructural studies of the catalytic core of the primate foamy virus (PFV-1) integraseA Crystal Structure of the Catalytic Core Domain of an Avian Sarcoma and Leukemia Virus Integrase Suggests an Alternate Dimeric AssemblyUltrahigh-resolution crystal structures of Z-DNA in complex with Mn(2+) and Zn(2+) ionsThe catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutantBinding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activityStructure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitorThree new structures of the core domain of HIV-1 integrase: an active site that binds magnesiumStructural basis for inactivating mutations and pH-dependent activity of avian sarcoma virus integraseThree metal ions at the active site of the Tetrahymena group I ribozymeUnprocessed viral DNA could be the primary target of the HIV-1 integrase inhibitor raltegravirMutations of acidic residues in RAG1 define the active site of the V(D)J recombinaseDissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysisStructural determinants of metal-induced conformational changes in HIV-1 integrase.Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures.Architecture of a full-length retroviral integrase monomer and dimer, revealed by small angle X-ray scattering and chemical cross-linkingSynthesis and structures of soluble magnesium and zinc carboxylates containing intramolecular NH···O hydrogen bonds in nonpolar solvents.An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase.Mapping the epitope of an inhibitory monoclonal antibody to the C-terminal DNA-binding domain of HIV-1 integrase.Targeting Tn5 transposase identifies human immunodeficiency virus type 1 inhibitors.Mode of inhibition of HIV-1 Integrase by a C-terminal domain-specific monoclonal antibody.An unusual helix turn helix motif in the catalytic core of HIV-1 integrase binds viral DNA and LEDGF.Retroviral DNA integration.Use of patient-derived human immunodeficiency virus type 1 integrases to identify a protein residue that affects target site selectionTransposase makes critical contacts with, and is stimulated by, single-stranded DNA at the P element termini in vitro.The same two monomers within a MuA tetramer provide the DDE domains for the strand cleavage and strand transfer steps of transposition.Rag-1 mutations associated with B-cell-negative scid dissociate the nicking and transesterification steps of V(D)J recombination.Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes.Tn5 transposase active site mutations suggest position of donor backbone DNA in synaptic complex.Molecular dynamics studies on the HIV-1 integrase catalytic domain.Comparison of multiple molecular dynamics trajectories calculated for the drug-resistant HIV-1 integrase T66I/M154I catalytic domain.HIV integrase, a brief overview from chemistry to therapeutics.An amino acid in the central catalytic domain of three retroviral integrases that affects target site selection in nonviral DNA.Targeting HIV-1 integrase.Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination.Patterns of sequence conservation at termini of long terminal repeat (LTR) retrotransposons and DNA transposons in the human genome: lessons from phage Mu.
P2860
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P2860
The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The catalytic domain of avian ...... e presence of divalent cations
@ast
The catalytic domain of avian ...... e presence of divalent cations
@en
The catalytic domain of avian ...... e presence of divalent cations
@nl
type
label
The catalytic domain of avian ...... e presence of divalent cations
@ast
The catalytic domain of avian ...... e presence of divalent cations
@en
The catalytic domain of avian ...... e presence of divalent cations
@nl
prefLabel
The catalytic domain of avian ...... e presence of divalent cations
@ast
The catalytic domain of avian ...... e presence of divalent cations
@en
The catalytic domain of avian ...... e presence of divalent cations
@nl
P2093
P1433
P1476
The catalytic domain of avian ...... e presence of divalent cations
@en
P2093
A M Skalka
A Wlodawer
J Alexandratos
P356
10.1016/S0969-2126(96)00012-3
P577
1996-01-01T00:00:00Z