Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
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Monoubiquitylation promotes mitochondrial p53 translocationGlioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressorStructural insights into the transcription-independent apoptotic pathway of p53PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosisThe DNA-binding domain mediates both nuclear and cytosolic functions of p53Fatal liaisons of p53 with Bax and BakSolution structure and binding specificity of the p63 DNA binding domainThe p53 core domain is a molten globule at low pH: functional implications of a partially unfolded structure.BclxL changes conformation upon binding to wild-type but not mutant p53 DNA binding domain.Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.Beyond effector caspase inhibition: Bcl2L12 neutralizes p53 signaling in glioblastoma.Bcl2's flexible loop domain regulates p53 binding and survivalMdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemiaPin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis.Mediation of the antiapoptotic activity of Bcl-xL protein upon interaction with VDAC1 proteinNuclear EGFR impairs ASPP2-p53 complex-induced apoptosis by inducing SOS1 expression in hepatocellular carcinomaDissecting p53-dependent apoptosis.Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domainVersatile functions of p53 protein in multicellular organismsMolecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterizationThe p53 family and programmed cell deathThe mitochondrial p53 pathway.Structural biology of the Bcl-2 family and its mimicry by viral proteinsComputationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.The relevance of protein-protein interactions for p53 function: the CPE contribution.p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies.Therapeutic strategies for head and neck cancer based on p53 status.Many players in BCL-2 family affairs.The cytoplasmic side of p53's oncosuppressive activities.Discoveries and controversies in BCL-2 protein-mediated apoptosis.The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression.Mitochondrial death functions of p53.Nicotine-induced damages in testicular tissue of rats; evidences for bcl-2, p53 and caspase-3 expression.Evaluation and Elucidation Studies of Natural Aglycones for Anticancer Potential using Apoptosis-Related Markers: An In silico Study.The p53-Bcl-2 connection.Mitochondrial p53 mediates a transcription-independent regulation of cell respiration and interacts with the mitochondrial F₁F0-ATP synthase.BCL2 mutations in diffuse large B-cell lymphoma.Protein-protein interactions: A PUMA mechanism unfolds.Comparative biophysical characterization of p53 with the pro-apoptotic BAK and the anti-apoptotic BCL-xL.Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.
P2860
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P2860
Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
@ast
Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
@en
type
label
Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
@ast
Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
@en
prefLabel
Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
@ast
Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
@en
P2093
P2860
P1433
P1476
Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
@en
P2093
Andrew M Petros
Angelo Gunasekera
Edward T Olejniczak
P2860
P304
P356
10.1016/S0014-5793(04)00059-6
P407
P577
2004-02-01T00:00:00Z