A rapid library screen for tailoring beta-peptide structure and function.
about
Evaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 DomainFoldamers as versatile frameworks for the design and evolution of functionA foldamer-dendrimer conjugate neutralizes synaptotoxic β-amyloid oligomersTowards vast libraries of scaffold-diverse, conformationally constrained oligomers.Biophysical and structural characterization of a robust octameric beta-peptide bundleOptimized protocols for the isolation of specific protein-binding peptides or peptoids from combinatorial libraries displayed on beads.Synthesis, screening, and sequencing of cysteine-rich one-bead one-compound peptide libraries.Comparison of design strategies for promotion of beta-peptide 14-helix stability in water.Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions.Stabilisation of Peptide foldamers in an aqueous medium by incorporation of azapeptide building blocks.De Novo Modular Development of a Foldameric Protein-Protein Interaction Inhibitor for Separate Hot Spots: A Dynamic Covalent Assembly Approach.Bridged beta(3)-peptide inhibitors of p53-hDM2 complexation: correlation between affinity and cell permeability.The rise, fall and reinvention of combinatorial chemistry.Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated α-synuclein.Beta-peptides with improved affinity for hDM2 and hDMX.Positional screening and NMR structure determination of side-chain-to-side-chain cyclized β3-peptides.Mini review: protein-protein interactions in transcription: a fertile ground for helix mimetics.Cell-permeable beta-peptide inhibitors of p53/hDM2 complexationSequencing of oligourea foldamers by tandem mass spectrometry.Specificity profiling of protein-binding domains using one-bead-one-compound Peptide libraries.γ-AApeptide-based small-molecule ligands that inhibit Aβ aggregation.Thermodynamic stability of beta-peptide helices and the role of cyclic residues.Recognition of antigen-specific B-cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates.Sophistication of foldamer form and function in vitro and in vivo.In Silico Improvement of beta3-peptide inhibitors of p53 x hDM2 and p53 x hDMXTranscriptional switches: chemical approaches to gene regulationStructure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.An overview of peptide and peptoid foldamers in medicinal chemistry.A rationally designed aldolase foldamer.Identification of a beta3-peptide HIV fusion inhibitor with improved potency in live cells.Native like helices in a specially designed β peptide in the gas phase.Positive allostery in metal ion binding by a cooperatively folded β-peptide bundle.Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling.Unique α,β- and α,α,β,β-Peptide Foldamers Based on cis-β-Aminocyclopentanecarboxylic Acid
P2860
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P2860
A rapid library screen for tailoring beta-peptide structure and function.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
A rapid library screen for tailoring beta-peptide structure and function.
@ast
A rapid library screen for tailoring beta-peptide structure and function.
@en
type
label
A rapid library screen for tailoring beta-peptide structure and function.
@ast
A rapid library screen for tailoring beta-peptide structure and function.
@en
prefLabel
A rapid library screen for tailoring beta-peptide structure and function.
@ast
A rapid library screen for tailoring beta-peptide structure and function.
@en
P2093
P2860
P356
P1476
A rapid library screen for tailoring beta-peptide structure and function.
@en
P2093
Alanna Schepartz
Elizabeth A Harker
Joshua A Kritzer
Nathan W Luedtke
P2860
P304
14584-14585
P356
10.1021/JA055050O
P407
P577
2005-10-01T00:00:00Z