Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo
about
Induction of G2 arrest and binding to cyclophilin A are independent phenotypes of human immunodeficiency virus type 1 VprHuman immunodeficiency virus type 1 Vpr induces G2 checkpoint activation by interacting with the splicing factor SAP145HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1Activation of the DNA Damage Response by RNA VirusesFormation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrestHow SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest.HTLV-1 Rex Tunes the Cellular Environment Favorable for Viral ReplicationThe papillomavirus E1 helicase activates a cellular DNA damage response in viral replication fociHIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANTHIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.Interactions with DCAF1 and DDB1 in the CRL4 E3 ubiquitin ligase are required for Vpr-mediated G2 arrest.Vpr-host interactions during HIV-1 viral life cycle.HIV-1 Vpr and G2 cell cycle arrest.Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R.The host-pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domainsModulation of NKG2D-mediated cytotoxic functions of natural killer cells by viral protein R from HIV-1 primary isolates.Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development.HIV-1 viral protein R downregulates Ebp1 and stabilizes p53 in glioblastoma U87MG cells.HIV-1 Vpr induces the degradation of ZIP and sZIP, adaptors of the NuRD chromatin remodeling complex, by hijacking DCAF1/VprBP.Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation.Defining the interactions and role of DCAF1/VPRBP in the DDB1-cullin4A E3 ubiquitin ligase complex engaged by HIV-1 Vpr to induce a G2 cell cycle arrest.Host factors that control long terminal repeat retrotransposons in Saccharomyces cerevisiae: implications for regulation of mammalian retrovirusesDNA-damage response pathways triggered by viral replication.Human immunodeficiency virus type 1 Vpr induces cell cycle G2 arrest through Srk1/MK2-mediated phosphorylation of Cdc2514-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 VprHuman immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.HIV-1 Vpr: mechanisms of G2 arrest and apoptosis.Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 RecruitmentLINE-1 retrotransposable element DNA accumulates in HIV-1-infected cells.Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variantsVpr expression abolishes the capacity of HIV-1 infected cells to repair uracilated DNA.Viral protein R upregulates expression of ULBP2 on uninfected bystander cells during HIV-1 infection of primary CD4+ T lymphocytesHIV-1 Vpr Protein Induces Proteasomal Degradation of Chromatin-associated Class I HDACs to Overcome Latent Infection of Macrophages.HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells.SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr).Vpr Enhances Tumor Necrosis Factor Production by HIV-1-Infected T Cells.The HIV-1 Vpr Protein: A Multifaceted Target for Therapeutic Intervention.Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo.HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrestHIV-1 accessory proteins: VpR.
P2860
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P2860
Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Activation of the ATR pathway ...... t binding to chromatin in vivo
@ast
Activation of the ATR pathway ...... t binding to chromatin in vivo
@en
type
label
Activation of the ATR pathway ...... t binding to chromatin in vivo
@ast
Activation of the ATR pathway ...... t binding to chromatin in vivo
@en
prefLabel
Activation of the ATR pathway ...... t binding to chromatin in vivo
@ast
Activation of the ATR pathway ...... t binding to chromatin in vivo
@en
P2093
P2860
P1433
P1476
Activation of the ATR pathway ...... t binding to chromatin in vivo
@en
P2093
Erik S Zimmerman
Junjie Chen
Vicente Planelles
P2860
P304
15443-15451
P356
10.1128/JVI.79.24.15443-15451.2005
P50
P577
2005-12-01T00:00:00Z