Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures.
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The origin and evolution of mutations in acute myeloid leukemiaReduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha.MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy-lysosomal pathway in acute promyelocytic leukemia.PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progressionExpression of a bcr-1 isoform of RARalpha-PML does not affect the penetrance of acute promyelocytic leukemia or the acquisition of an interstitial deletion on mouse chromosome 2Treatment-influenced associations of PML-RARα mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia.Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia.Chromatin modifications induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip.Applications of microarray technology to Acute Myelogenous LeukemiaRARA fusion genes in acute promyelocytic leukemia: a review.Identification of a molecular signature for leukemic promyelocytes and their normal counterparts: Focus on DNA repair genes.Stage specific gene expression of serpins and their cognate proteases during myeloid differentiation.Commonly dysregulated genes in murine APL cells.Opinion: how patients have benefited from mouse models of acute promyelocytic leukaemia.
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Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on December 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Expression profiling of murine ...... endent progression signatures.
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Expression profiling of murine ...... endent progression signatures.
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type
label
Expression profiling of murine ...... endent progression signatures.
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Expression profiling of murine ...... endent progression signatures.
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Expression profiling of murine ...... endent progression signatures.
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Expression profiling of murine ...... endent progression signatures.
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P2860
P1476
Expression profiling of murine ...... endent progression signatures.
@en
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Andrew A Lane
John S Park
Matthew J Walter
Rakesh Nagarajan
Timothy J Ley
William D Shannon
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P304
10882-10893
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10.1128/MCB.24.24.10882-10893.2004
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2004-12-01T00:00:00Z