Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.
about
Tumor cells positive and negative for the common cancer stem cell markers are capable of initiating tumor growth and generating both progeniesLPS independent activation of the pro-inflammatory receptor Trem1 by C/EBPε in granulocytesIdentification of nuclear-enriched miRNAs during mouse granulopoiesisDown-regulation of the expression of CCAAT/enhancer binding protein α gene in cervical squamous cell carcinomaBCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cellsTumor-initiating cells are enriched in CD44(hi) population in murine salivary gland tumor.A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.Cancer stem cells: a stride towards cancer cure?Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL.Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia.Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemiaExpression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA miceCyclic AMP responsive element binding proteins are involved in 'emergency' granulopoiesis through the upregulation of CCAAT/enhancer binding protein βPML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.The CEBPA gene is down-regulated in acute promyelocytic leukemia and its upstream promoter, but not the core promoter, is highly methylatedSTAT activation status differentiates leukemogenic from non-leukemogenic stem cells in AML and is suppressed by arsenic in t(6;9)-positive AMLDeveloping ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention.Functional and structural insights into ASB2alpha, a novel regulator of integrin-dependent adhesion of hematopoietic cellsComparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance.Establishment of a humanized APL model via the transplantation of PML-RARA-transduced human common myeloid progenitors into immunodeficient mice.PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway.The peripheral nervous system supports blood cell homing and survival in the Drosophila larva.A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2.Preventing clonal evolutionary processes in cancer: Insights from mathematical models.Non-steady-state hematopoiesis regulated by the C/EBPβ transcription factor.Acute myeloid leukemia stem cells and CD33-targeted immunotherapyContext Matters: Distinct Disease Outcomes as a Result of Crebbp Hemizygosity in Different Mouse Bone Marrow CompartmentsErythroid lineage-restricted expression of Jak2V617F is sufficient to induce a myeloproliferative disease in mice8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation.MPN patients harbor recurrent truncating mutations in transcription factor NF-E2Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation.Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA.Single-cell analysis of mixed-lineage states leading to a binary cell fate choice.Differential requirement for wild-type Flt3 in leukemia initiation among mouse models of human leukemia.Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism.ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype.Interplay of protein misfolding pathway and unfolded-protein response in acute promyelocytic leukemia.Dynamics of epigenetic modifications in leukemia.Function of oncogenes in cancer development: a changing paradigm.Cancer Stem Cells: A Moving Target
P2860
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P2860
Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification of a myeloid co ...... acute promyelocytic leukemia.
@ast
Identification of a myeloid co ...... acute promyelocytic leukemia.
@en
Identification of a myeloid co ...... acute promyelocytic leukemia.
@nl
type
label
Identification of a myeloid co ...... acute promyelocytic leukemia.
@ast
Identification of a myeloid co ...... acute promyelocytic leukemia.
@en
Identification of a myeloid co ...... acute promyelocytic leukemia.
@nl
prefLabel
Identification of a myeloid co ...... acute promyelocytic leukemia.
@ast
Identification of a myeloid co ...... acute promyelocytic leukemia.
@en
Identification of a myeloid co ...... acute promyelocytic leukemia.
@nl
P2093
P2860
P50
P1433
P1476
Identification of a myeloid co ...... n acute promyelocytic leukemia
@en
P2093
Alexander Ebralidze
Amy J Wagers
Barbara A Santana-Lemos
Donna Neuberg
Elena Levantini
Florence C Guibal
Hideyo Hirai
Meritxell Alberich-Jorda
P2860
P304
P356
10.1182/BLOOD-2008-10-182071
P407
P577
2009-10-01T00:00:00Z