Treatment of liver ischemia-reperfusion injury by limiting thrombospondin-1/CD47 signaling.
about
Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factorsRadioprotection in normal tissue and delayed tumor growth by blockade of CD47 signalingActivated CD47 regulates multiple vascular and stress responses: implications for acute kidney injury and its managementCD47 knockout mice exhibit improved recovery from spinal cord injury.CD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interestSignaling and stress: The redox landscape in NOS2 biologyMolecular regulation of tumor angiogenesis and perfusion via redox signaling.Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury.Blockade of CD47 increases survival of mice exposed to lethal total body irradiationThrombospondin-1 inhibition of vascular smooth muscle cell responses occurs via modulation of both cAMP and cGMP.Age-associated induction of cell membrane CD47 limits basal and temperature-induced changes in cutaneous blood flow.Disruption of thrombospondin-2 accelerates ischemic fracture healing.CD47 in the tumor microenvironment limits cooperation between antitumor T-cell immunity and radiotherapyAge-dependent regulation of skeletal muscle mitochondria by the thrombospondin-1 receptor CD47.Thrombospondin-1 and CD47 signaling regulate healing of thermal injury in mice.CD47 blockade reduces ischemia-reperfusion injury and improves outcomes in a rat kidney transplant model.The matricellular protein thrombospondin-1 globally regulates cardiovascular function and responses to stress via CD47.Therapeutic Targeting of CD47 to Modulate Tissue Responses to Ischemia and Radiation.CD47 blockade reduces ischemia/reperfusion injury and improves survival in a rat liver transplantation model.Activation of parenchymal CD47 promotes renal ischemia-reperfusion injury.CD47 deficiency confers cell and tissue radioprotection by activation of autophagy.Secreted Thrombospondin-1 Regulates Macrophage Interleukin-1β Production and Activation through CD47.CD47 signaling pathways controlling cellular differentiation and responses to stress.Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapiesThrombospondin-1/CD47 blockade following ischemia-reperfusion injury is tissue protective.Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow.Thrombospondin-1 and CD47 regulation of cardiac, pulmonary and vascular responses in health and disease.Thrombospondin-1, free radicals, and the coronary microcirculation: the aging conundrum.Regulation of cellular redox signaling by matricellular proteins in vascular biology, immunology, and cancerMatricellular protein thrombospondin-1 in pulmonary hypertension: multiple pathways to disease.CD47 blockade reduces ischemia/reperfusion injury in donation after cardiac death rat kidney transplantation.CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs.Computer Simulation of TSP1 Inhibition of VEGF-Akt-eNOS: An Angiogenesis Triple Threat.CD47
P2860
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P2860
Treatment of liver ischemia-reperfusion injury by limiting thrombospondin-1/CD47 signaling.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Treatment of liver ischemia-re ...... rombospondin-1/CD47 signaling.
@ast
Treatment of liver ischemia-re ...... rombospondin-1/CD47 signaling.
@en
type
label
Treatment of liver ischemia-re ...... rombospondin-1/CD47 signaling.
@ast
Treatment of liver ischemia-re ...... rombospondin-1/CD47 signaling.
@en
prefLabel
Treatment of liver ischemia-re ...... rombospondin-1/CD47 signaling.
@ast
Treatment of liver ischemia-re ...... rombospondin-1/CD47 signaling.
@en
P2093
P2860
P1433
P1476
Treatment of liver ischemia-re ...... rombospondin-1/CD47 signaling.
@en
P2093
Jeff S Isenberg
Justin B Maxhimer
Maria Tsokos
Perlita Powers
William A Frazier
P2860
P304
P356
10.1016/J.SURG.2008.07.009
P407
P577
2008-09-02T00:00:00Z