Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
about
Aβ42-oligomer Interacting Peptide (AIP) neutralizes toxic amyloid-β42 species and protects synaptic structure and function.8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applicationsDihydroxybenzoic acid isomers differentially dissociate soluble biotinyl-Aβ(1-42) oligomers.Structure-activity relationships of organofluorine inhibitors of β-amyloid self-assembly.The concept of privileged structures in rational drug design: focus on acridine and quinoline scaffolds in neurodegenerative and protozoan diseases.Diaryl hydrazones as multifunctional inhibitors of amyloid self-assembly.Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's diseaseBiometals and their therapeutic implications in Alzheimer's disease.Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer's Disease.Rational approach to an antiprion compound with a multiple mechanism of action.Aβ(1-42) assembly in the presence of scyllo-inositol derivatives: identification of an oxime linkage as important for the development of assembly inhibitors.Effect of 8-hydroxyquinoline and derivatives on human neuroblastoma SH-SY5Y cells under high glucose.Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones.A randomized, exploratory molecular imaging study targeting amyloid β with a novel 8-OH quinoline in Alzheimer's disease: The PBT2-204 IMAGINE study.Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer's disease agents.Nucleoside-2',3'/3',5'-bis(thio)phosphate antioxidants are also capable of disassembly of amyloid beta42-Zn(ii)/Cu(ii) aggregates via Zn(ii)/Cu(ii)-chelation.Nucleoside-5'-phosphorothioate analogues are biocompatible antioxidants dissolving efficiently amyloid beta-metal ion aggregatesThe Amyloid-β Peptide in Amyloid Formation Processes: Interactions with Blood Proteins and Naturally Occurring Metal Ions
P2860
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P2860
Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
@ast
Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
@en
type
label
Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
@ast
Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
@en
prefLabel
Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
@ast
Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
@en
P2093
P2860
P1433
P1476
Clioquinol and other hydroxyquinoline derivatives inhibit Abeta(1-42) oligomer assembly.
@en
P2093
Corinne E Augelli-Szafran
Harry LeVine
John A Walker
Qunxing Ding
Randal S Voss
P2860
P304
P356
10.1016/J.NEULET.2009.08.002
P407
P577
2009-08-05T00:00:00Z