Neutrophil elastase is important for PML-retinoic acid receptor alpha activities in early myeloid cells.
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Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastaseELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETOLocation of NLS-RARα protein in NB4 cell and nude mice.Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha.The PML domain of PML-RARα blocks senescence to promote leukemiaA protease-resistant PML-RAR{alpha} has increased leukemogenic potential in a murine model of acute promyelocytic leukemiaSynthesis and evaluation of bisbenzylidenedioxotetrahydrothiopranones as activators of endoplasmic reticulum (ER) stress signaling pathways and apoptotic cell death in acute promyelocytic leukemic cells.Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA micePML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.Neutrophil elastase in cyclic and severe congenital neutropenia.Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice.Neutrophil elastase and its therapeutic effect on leukemia cells.Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy.ELANE mutations in cyclic and severe congenital neutropenia: genetics and pathophysiologyPML(NLS(-)) inhibits cell apoptosis and promotes proliferation in HL-60 cells.Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling.IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβNLS-RARα Inhibits the Effects of All-trans Retinoic Acid on NB4 Cells by Interacting with P38α MAPK.Effect of GINS2 on proliferation and apoptosis in leukemic cell line.Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures.NLS‑RARα modulates acute promyelocytic leukemia NB4 cell proliferation and differentiation via the PI3K/AKT pathway.Interplay of protein misfolding pathway and unfolded-protein response in acute promyelocytic leukemia.Curcumin analogues with potent and selective anti-proliferative activity on acute promyelocytic leukemia: involvement of accumulated misfolded nuclear receptor co-repressor (N-CoR) protein as a basis for selective activity.Stage specific gene expression of serpins and their cognate proteases during myeloid differentiation.Hop cleavage and function in granzyme B-induced apoptosis.PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors.Commonly dysregulated genes in murine APL cells.PML(NLS¯) protein: A novel marker for the early diagnosis of acute promyelocytic leukemia.
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P2860
Neutrophil elastase is important for PML-retinoic acid receptor alpha activities in early myeloid cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Neutrophil elastase is importa ...... vities in early myeloid cells.
@ast
Neutrophil elastase is importa ...... vities in early myeloid cells.
@en
Neutrophil elastase is importa ...... vities in early myeloid cells.
@nl
type
label
Neutrophil elastase is importa ...... vities in early myeloid cells.
@ast
Neutrophil elastase is importa ...... vities in early myeloid cells.
@en
Neutrophil elastase is importa ...... vities in early myeloid cells.
@nl
prefLabel
Neutrophil elastase is importa ...... vities in early myeloid cells.
@ast
Neutrophil elastase is importa ...... vities in early myeloid cells.
@en
Neutrophil elastase is importa ...... vities in early myeloid cells.
@nl
P2860
P1476
Neutrophil elastase is importa ...... vities in early myeloid cells.
@en
P2093
Andrew A Lane
Timothy J Ley
P2860
P356
10.1128/MCB.25.1.23-33.2005
P407
P577
2005-01-01T00:00:00Z