Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease.
about
Role of cerebral cortex in the neuropathology of Huntington's diseaseMouse models of polyglutamine diseases: review and data table. Part IGenomic analysis of wig-1 pathwaysAmyloid oligomer neurotoxicity, calcium dysregulation, and lipid raftsSystematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.Alterations in cortical excitation and inhibition in genetic mouse models of Huntington's disease.Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteinsSerines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.Parvalbumin deficiency and GABAergic dysfunction in mice lacking PGC-1alphaIs synaptic loss a unique hallmark of Alzheimer's disease?Genetic LRRK2 models of Parkinson's disease: Dissecting the pathogenic pathway and exploring clinical applicationsCortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington's diseaseAltered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington's disease.Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.Reduced activity of AMP-activated protein kinase protects against genetic models of motor neuron disease.A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease.Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells.Establishing a physiological environment for visualized in vitro brain slice recordings by increasing oxygen supply and modifying aCSF content.Genetic mouse models of Huntington's disease: focus on electrophysiological mechanisms.Huntington's disease: can mice lead the way to treatment?Screening of therapeutic strategies for Huntington's disease in YAC128 transgenic mice.Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.Using non-coding small RNAs to develop therapies for Huntington's disease.Corticostriatal dysfunction and glutamate transporter 1 (GLT1) in Huntington's disease: interactions between neurons and astrocytes.Dopamine imbalance in Huntington's disease: a mechanism for the lack of behavioral flexibility.Cognitive dysfunction in Huntington's disease: mechanisms and therapeutic strategies beyond BDNF.Dysregulation of Corticostriatal Connectivity in Huntington's Disease: A Role for Dopamine ModulationDysregulation of corticostriatal ascorbate release and glutamate uptake in transgenic models of Huntington's disease.Cortical interneuron loss and symptom heterogeneity in Huntington disease.Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease.Disrupted GABAAR trafficking and synaptic inhibition in a mouse model of Huntington's disease.Impaired long-term potentiation in the prefrontal cortex of Huntington's disease mouse models: rescue by D1 dopamine receptor activation.Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic mice.Disease-modifying effects of ganglioside GM1 in Huntington's disease models.
P2860
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P2860
Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Progressive synaptic pathology ...... model of Huntington's disease.
@ast
Progressive synaptic pathology ...... model of Huntington's disease.
@en
Progressive synaptic pathology ...... model of Huntington's disease.
@nl
type
label
Progressive synaptic pathology ...... model of Huntington's disease.
@ast
Progressive synaptic pathology ...... model of Huntington's disease.
@en
Progressive synaptic pathology ...... model of Huntington's disease.
@nl
prefLabel
Progressive synaptic pathology ...... model of Huntington's disease.
@ast
Progressive synaptic pathology ...... model of Huntington's disease.
@en
Progressive synaptic pathology ...... model of Huntington's disease.
@nl
P2093
P2860
P1433
P1476
Progressive synaptic pathology ...... model of Huntington's disease.
@en
P2093
P2860
P304
P356
10.1016/J.NEUROSCIENCE.2008.09.020
P407
P50
P577
2008-09-18T00:00:00Z