Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites. - Wikidata - wikimedia - TriplyDB

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

http://www.wikidata.org/entity/Q33589782

about

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair Multiple roles of ATM in monitoring and maintaining DNA integrity FOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistance The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator Human Ku70/80 protein blocks exonuclease 1-mediated DNA resection in the presence of human Mre11 or Mre11/Rad50 protein complex.Structures of closed and open conformations of dimeric human ATM Autophosphorylation and ATM activation: additional sites add to the complexity.Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks.ATR autophosphorylation as a molecular switch for checkpoint activation.Inducible response required for repair of low-dose radiation damage in human fibroblasts.The MRN complex in double-strand break repair and telomere maintenance.Persistently bound Ku at DNA ends attenuates DNA end resection and homologous recombination Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance Phosphatases in the cellular response to DNA damage.Replication stress by Py-Im polyamides induces a non-canonical ATR-dependent checkpoint response.ATM signalling and cancer.DNA double-strand break signaling and human disorders.Loss of ATM kinase activity leads to embryonic lethality in mice Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism.Homologous recombination repair signaling in chemical carcinogenesis: prolonged particulate hexavalent chromium exposure suppresses the Rad51 response in human lung cells.Oligomerization of MDC1 protein is important for proper DNA damage response Whole genome RNAi screens reveal a critical role of REV3 in coping with replication stress.Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses.Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions Extracellular signal-regulated kinases modulate DNA damage response - a contributing factor to using MEK inhibitors in cancer therapy.INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells A p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion.Cellular mechanisms of zinc dysregulation: a perspective on zinc homeostasis as an etiological factor in the development and progression of breast cancer.A dual interaction between the DNA damage response protein MDC1 and the RAG1 subunit of the V(D)J recombinase Platelet-activating factor induces cell cycle arrest and disrupts the DNA damage response in mast cells Imaging of Fluorescently Tagged ATM Kinase at the Sites of DNA Double Strand Breaks.Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation.The ATM signaling network in development and disease.The shape of the radiation dose response for DNA double-strand break induction and repair.Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under ATM or p53 inhibition Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair ATM mediates pRB function to control DNMT1 protein stability and DNA methylation.NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex.Linking JNK Activity to the DNA Damage Response.

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P2860

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

http://www.wikidata.org/entity/Q33589782

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@ast

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@en

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@nl

type

label

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@ast

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@en

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@nl

prefLabel

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@ast

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@en

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@nl

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Journal of Cell Biology

P1476

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.

@en

P2093

Anthony J Davis

http://www.w3.org/2001/XMLSchema#string

David J Chen

http://www.w3.org/2001/XMLSchema#string

Sairei So

http://www.w3.org/2001/XMLSchema#string

P2860

MDC1 is a mediator of the mammalian DNA damage checkpoint

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

Ku recruits XLF to DNA double-strand breaks

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

ATMIN defines an NBS1-independent pathway of ATM signalling

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunit

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977-990

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scholarly article

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10.1083/JCB.200906064

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7

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187

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2009-12-21T00:00:00Z

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40757182

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20026654

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2806275

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