Structure-based design, synthesis and biological evaluation of new N-carboxyphenylpyrrole derivatives as HIV fusion inhibitors targeting gp41.

Structure-based design, synthesis and biological evaluation of new N-carboxyphenylpyrrole derivatives as HIV fusion inhibitors targeting gp41.

Item
http://www.wikidata.org/entity/Q33638192
Identification of fragments targeting an alternative pocket on HIV-1 gp41 by NMR screening and similarity searching.Design and characterization of swapped-domain constructs of HIV-1 glycoprotein-41 as receptors for drug discovery.Enhanced potency of bivalent small molecule gp41 inhibitors.Biochemistry and biophysics of HIV-1 gp41 - membrane interactions and implications for HIV-1 envelope protein mediated viral-cell fusion and fusion inhibitor designIdentification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosisDevelopment of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41HIV microbicides: state-of-the-art and new perspectives on the development of entry inhibitors.De novo design: balancing novelty and confined chemical space.Approaches for identification of HIV-1 entry inhibitors targeting gp41 pocketSynthesis, Biological Evaluation and Molecular Docking Studies of Novel 4-Arylpyridin-1(4H)-yl) benzoic acid Derivatives as Anti-HIV-1 Agents.Artificial peptides conjugated with cholesterol and pocket-specific small molecules potently inhibit infection by laboratory-adapted and primary HIV-1 isolates and enfuvirtide-resistant HIV-1 strains.Small-molecule HIV-1 entry inhibitors targeting gp120 and gp41: a patent review (2010-2015).Development of indole compounds as small molecule fusion inhibitors targeting HIV-1 glycoprotein-41.An effective conjugation strategy for designing short peptide-based HIV-1 fusion inhibitors.Paramagnetic relaxation assisted docking of a small indole compound in the HIV-1 gp41 hydrophobic pocket
P2860

Structure-based design, synthesis and biological evaluation of new N-carboxyphenylpyrrole derivatives as HIV fusion inhibitors targeting gp41.

Item
http://www.wikidata.org/entity/Q33638192
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structure-based design, synthe ...... ion inhibitors targeting gp41.
@ast
Structure-based design, synthe ...... ion inhibitors targeting gp41.
@en
type
label
Structure-based design, synthe ...... ion inhibitors targeting gp41.
@ast
Structure-based design, synthe ...... ion inhibitors targeting gp41.
@en
prefLabel
Structure-based design, synthe ...... ion inhibitors targeting gp41.
@ast
Structure-based design, synthe ...... ion inhibitors targeting gp41.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
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P433
P478
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P577
P5875
P698
P932
P356
P1433
P1476
Structure-based design, synthe ...... ion inhibitors targeting gp41.
@en
P2093
P2860
P304
P31
P356
10.1016/J.BMCL.2009.10.139
P407
P433
P478
P50
P577
P5875
P698
P932