CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.
about
Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphataseIdentification of a carbonic anhydrase-like domain in the extracellular region of RPTP gamma defines a new subfamily of receptor tyrosine phosphatasesDistinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LARCloning and expression of a widely expressed receptor tyrosine phosphataseMPTP delta, a putative murine homolog of HPTP delta, is expressed in specialized regions of the brain and in the B-cell lineagecDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase familyReceptor tyrosine phosphatase R-PTP-kappa mediates homophilic bindingGene expressions of protein tyrosine phosphatases in regenerating rat liver and rat ascites hepatoma cellsExpression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell linesIntimate association of Thy-1 and the T-cell antigen receptor with the CD45 tyrosine phosphatase.CD148, a new membrane tyrosine phosphatase involved in leukocyte function.Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide.Amplification of T cell blastogenic responses in healthy individuals and patients with acquired immunodeficiency syndromeHuman placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins.Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase.Changes in CD45 isoform expression accompany antigen-induced murine T-cell activationCD4 and CD8 molecules can physically associate with the same T-cell receptor.Evidence for defective transmembrane signaling in B cells from patients with Wiskott-Aldrich syndrome.Identification and analysis of a novel human surface CD5- B lymphocyte subset producing natural antibodies.CD45 cell surface antigens are linked to stimulation of early human myeloid progenitor cells by interleukin 3 (IL-3), granulocyte/macrophage colony-stimulating factor (GM-CSF), a GM-CSF/IL-3 fusion protein, and mast cell growth factor (a c-kit liganAntibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cellsAggregation of lipid rafts accompanies signaling via the T cell antigen receptorSelective expression of CD45 isoforms on functional subpopulations of CD34+ hemopoietic cells from human bone marrow.Autoantibodies specific for different isoforms of CD45 in systemic lupus erythematosus.Lymphokine regulation of CD45R expression on human T cell clones.Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activationCD45 tyrosine phosphatase activity and membrane anchoring are required for T-cell antigen receptor signaling.CD8+ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuliSulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase C gamma 1CD5 is phosphorylated on tyrosine after stimulation of the T-cell antigen receptor complex.Receptor-type tyrosine phosphatase ligands: looking for the needle in the haystack.The c-src family of protein-tyrosine kinases.Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.CD3 stimulation causes phosphorylation of phospholipase C-gamma 1 on serine and tyrosine residues in a human T-cell line.A Simple, Versatile Antibody-Based Barcoding Method for Flow Cytometry.Association of CD8 with p56lck is required for early T cell signalling events.Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV).Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase.Evidence for involvement of glycoprotein-CD45 phosphatase in reversing glycoprotein-CD3-induced microtubule-associated protein-2 kinase activity in Jurkat T-cells.Induction of tyrosine phosphorylation and T-cell activation by vanadate peroxide, an inhibitor of protein tyrosine phosphatases.
P2860
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P2860
CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.
description
1988 nî lūn-bûn
@nan
1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
CD45 regulates signal transduc ...... tor molecules on T or B cells.
@ast
CD45 regulates signal transduc ...... tor molecules on T or B cells.
@en
type
label
CD45 regulates signal transduc ...... tor molecules on T or B cells.
@ast
CD45 regulates signal transduc ...... tor molecules on T or B cells.
@en
prefLabel
CD45 regulates signal transduc ...... tor molecules on T or B cells.
@ast
CD45 regulates signal transduc ...... tor molecules on T or B cells.
@en
P2093
P2860
P356
P1476
CD45 regulates signal transduc ...... tor molecules on T or B cells.
@en
P2093
E H Fischer
J A Ledbetter
P2860
P304
P356
10.1073/PNAS.85.22.8628
P407
P577
1988-11-01T00:00:00Z