Antibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cells
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Genetic engineering of T cells for adoptive immunotherapyStimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cellsSignal transduction by CD28 costimulatory receptor on T cells. B7-1 and B7-2 regulation of tyrosine kinase adaptor moleculesTwo distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase associationThe role of Tec protein-tyrosine kinase in T cell signalingCD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line.Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins.Developmental regulation of a murine T-cell-specific tyrosine kinase gene, TskThe interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65.Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signalingThe combination of anti-B7 monoclonal antibody and cyclosporin A induces alloantigen-specific anergy during a primary mixed lymphocyte reaction.Itk negatively regulates induction of T cell proliferation by CD28 costimulation.Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells.T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo.itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.Inhibition of activation of transcription factor AP-1 by CD28 signalling in human T-cells.Molecular regulation of the IL-2 gene: rheostatic control of the immune system.IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenaseCD28: a signalling perspective.Differential phosphorylation of the T lymphocyte costimulatory receptor CD28. Activation-dependent changes and regulation by protein kinase C.Functional LCK Is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK.CD80, CD86 and CD40 provide accessory signals in a multiple-step T-cell activation model.Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage.The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase.Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity.The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras.A cellular platform for the evaluation of immune checkpoint molecules.Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK.Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28.Tyrosine phosphorylation of a novel 100-kDa protein coupled to CD28 in resting human T cells is enhanced by a signal through TCR/CD3 complex.Cyclic AMP Sensitive Signalling by the CD28 Marker Requires Concomitant Stimulation by the T-Cell Antigen Receptor (TCR/CD3) Complex
P2860
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P2860
Antibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cells
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Antibody and B7/BB1-mediated l ...... osphorylation in human T cells
@ast
Antibody and B7/BB1-mediated l ...... osphorylation in human T cells
@en
type
label
Antibody and B7/BB1-mediated l ...... osphorylation in human T cells
@ast
Antibody and B7/BB1-mediated l ...... osphorylation in human T cells
@en
prefLabel
Antibody and B7/BB1-mediated l ...... osphorylation in human T cells
@ast
Antibody and B7/BB1-mediated l ...... osphorylation in human T cells
@en
P2093
P2860
P356
P1476
Antibody and B7/BB1-mediated l ...... osphorylation in human T cells
@en
P2093
Fletcher MC
Freeman GJ
Ledbetter JA
Thompson CB
Vandenberghe P
P2860
P304
P356
10.1084/JEM.175.4.951
P407
P577
1992-04-01T00:00:00Z