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Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

http://www.wikidata.org/entity/Q33679727

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Defining the domains of human polynucleotide phosphorylase (hPNPaseOLD-35) mediating cellular senescence.Differential protein expression, DNA binding and interaction with SV40 large tumour antigen implicate the p63-family of proteins in replicative senescence Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity Telomere length predicts replicative capacity of human fibroblasts Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division.Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells.High telomerase activity correlates with the stabilities of genome and DNA ploidy in renal cell carcinoma Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.Growth and aging: a common molecular mechanism.Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice.Tumor suppression by p53: making cells senescent.ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts.A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis.Oxidative DNA damage and senescence of human diploid fibroblast cells.A potential role for NEDD1 and the centrosome in senescence of mouse embryonic fibroblasts.Regulation of senescence in cancer and aging.Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes Cellular senescence.The biological clock that measures the mitotic life-span of mouse embryo fibroblasts continues to function in the presence of simian virus 40 large tumor antigen.A mouse model of accelerated liver aging caused by a defect in DNA repair The intrinsic stiffness of human trabecular meshwork cells increases with senescence.Senescence and quiescence induced compromised function in cultured macrophages Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span In situ analysis of changes in telomere size during replicative aging and cell transformation.The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1 Rat embryo fibroblasts immortalized with simian virus 40 large T antigen undergo senescence upon its inactivation Induction of replicative senescence by 5-azacytidine: fundamental cell kinetic differences between human diploid fibroblasts and NIH-3T3 cells.Alterations to nuclear architecture and genome behavior in senescent cells.Does a sentinel or a subset of short telomeres determine replicative senescence?Gadd45b deficiency promotes premature senescence and skin aging.Developing top down proteomics to maximize proteome and sequence coverage from cells and tissues.Tissue formation and tissue engineering through host cell recruitment or a potential injectable cell-based biocomposite with replicative potential: Molecular mechanisms controlling cellular senescence and the involvement of controlled transient telo Unbalanced Growth, Senescence and Aging.Duplicated chromosomal fragments stabilize shortened telomeres in normal human IMR-90 cells before transition to senescence.Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies.SV40 T antigen increases the expression and activities of p34cdc2, cyclin A, and cyclin B prior to immortalization of human diploid fibroblasts.Differential regulation of cyclin A, cyclin B and p21 concentrations in a growth-restricted human fibroblast cell line

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Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

http://www.wikidata.org/entity/Q33679727

description

1988 nî lūn-bûn

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1988 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1988 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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1988年の論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年论文

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name

Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

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Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

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type

label

Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

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Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

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prefLabel

Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

@ast

Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

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Proceedings of the National Academy of Sciences of the United States of America

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Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

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D Rush

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J L Ellsworth

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R T Schimke

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S W Sherwood

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P2860

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Aging of human fibroblasts in vitro. Correlations between DNA synthetic ability and cell size.

Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos

Expression of cell cycle-dependent genes in young and senescent WI-38 fibroblasts

ANEUPLOIDY IN THE DEGENERATIVE PHASE OF SERIAL CULTIVATION OF HUMAN CELL STRAINS

Regulation of human fibroblast growth rate by both noncycling cell fraction transition probability is shown by growth in 5-bromodeoxyuridine followed by Hoechst 33258 flow cytometry.

Effect of cycloheximide on development of methotrexate resistance of Chinese hamster ovary cells treated with inhibitors of DNA synthesis.

Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine.

Membrane-associated inhibitor of DNA synthesis in senescent human diploid fibroblasts: characterization and comparison to quiescent cell inhibitor.

Prematurely condensed chromosomes of dividing and non-dividing cells in aging human cell cultures.

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