Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.
about
Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activityGenes other than BRCA1 and BRCA2 involved in breast cancer susceptibilityCommon ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case-control studyThe ATR-p53 pathway is suppressed in noncycling normal and malignant lymphocytesActivation and activities of the p53 tumour suppressor proteinChemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased CarcinogenesisUV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.Cancer risk and the ATM gene: a continuing debate.High-resolution melting curve analysis for rapid detection of mutations in a Medaka TILLING library.Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40.ATM gene and lymphoid malignancies.Ataxia telangiectasia gene mutations in leukaemia and lymphoma.Manipulating the mammalian genome by homologous recombinationThe yeast TEL1 gene partially substitutes for human ATM in suppressing hyperrecombination, radiation-induced apoptosis and telomere shortening in A-T cells.DNA mismatch repair and infertilityIntestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity.Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator AvenEffects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice.ATM: sounding the double-strand break alarm.Experimental antioxidant therapy in ataxia telangiectasia.Dimer monomer transition and dimer re-formation play important role for ATM cellular function during DNA repair.Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrestThe radioprotective agent WR1065 protects cells from radiation damage by regulating the activity of the Tip60 acetyltransferasePathways to motor incoordination: the inherited ataxias.DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity.ATM haplotypes and breast cancer risk in Jewish high-risk women.Disclosure of incidental findings from next-generation sequencing in pediatric genomic researchCellular responses to ionising radiation of AT heterozygotes: differences between missense and truncating mutation carriers.Oxidative Stress in Cancer-Prone Genetic Diseases in Pediatric Age: The Role of Mitochondrial DysfunctionATM mutations uniformly lead to ATM dysfunction in chronic lymphocytic leukemia: application of functional test using doxorubicin.Pancreatic adenocarcinoma: new strategies for successTip60: connecting chromatin to DNA damage signaling.Telomerase activity, apoptosis and cell cycle progression in ataxia telangiectasia lymphocytes expressing TCL1.Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.Activation of the kinase activity of ATM by retinoic acid is required for CREB-dependent differentiation of neuroblastoma cells.DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM.A new effector pathway links ATM kinase with the DNA damage response.ATM's leucine-rich domain and adjacent sequences are essential for ATM to regulate the DNA damage response.Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53.Spontaneously immortalized cell lines obtained from adult Atm null mice retain sensitivity to ionizing radiation and exhibit a mutational pattern suggestive of oxidative stress.
P2860
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P2860
Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.
@ast
Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.
@en
type
label
Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.
@ast
Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.
@en
prefLabel
Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.
@ast
Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.
@en
P2860
P1433
P1476
Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.
@en
P2093
P2860
P304
P356
10.1034/J.1399-0004.1999.550501.X
P577
1999-05-01T00:00:00Z