Hybrid lentivirus-transposon vectors with a random integration profile in human cells. - Wikidata - wikimedia - TriplyDB

Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

http://www.wikidata.org/entity/Q33713812

about

The Sleeping Beauty transposon system: a non-viral vector for gene therapy Gene therapy for hemophilia Driving DNA transposition by lentiviral protein transduction DNA transposon-based gene vehicles - scenes from an evolutionary drive Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein Sleeping beauty transposition from nonintegrating lentivirus.Hybrid lentivirus-phiC31-int-NLS vector allows site-specific recombination in murine and human cells but induces DNA damage.piggyBac transposon-mediated long-term gene expression in mice.The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor A new extensively characterised conditionally immortal muscle cell-line for investigating therapeutic strategies in muscular dystrophies Translating Sleeping Beauty transposition into cellular therapies: victories and challenges.Restoration of dystrophin expression using the Sleeping Beauty transposon.Understanding lentiviral vector chromatin targeting: working to reduce insertional mutagenic potential for gene therapy.Hybrid adeno-associated viral vectors utilizing transposase-mediated somatic integration for stable transgene expression in human cells.Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells.Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery Mobilization of DNA transposable elements from lentiviral vectors.Hybrid nonviral/viral vector systems for improved piggyBac DNA transposon in vivo delivery Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras.Zinc finger protein designed to target 2-long terminal repeat junctions interferes with human immunodeficiency virus integration.Targeted, homology-driven gene insertion in stem cells by ZFN-loaded 'all-in-one' lentiviral vectors.Integration profile and safety of an adenovirus hybrid-vector utilizing hyperactive sleeping beauty transposase for somatic integration.Human adipose derived mesenchymal stromal cells transduced with GFP lentiviral vectors: assessment of immunophenotype and differentiation capacity in vitro.Histone deacetylase inhibition rescues gene knockout levels achieved with integrase-defective lentiviral vectors encoding zinc-finger nucleases.Integration-deficient lentiviral vectors: a slow coming of age.DNA transposition by protein transduction of the piggyBac transposase from lentiviral Gag precursors Integrase-defective lentiviral vectors: progress and applications.Recent advances in lentiviral vector development and applications.Hybrid lentiviral vectors.Targeting the central nervous system with herpes simplex virus / Sleeping Beauty hybrid amplicon vectors.Viral hybrid vectors for somatic integration - are they the better solution?The Sleeping Beauty transposon system for clinical applications.Recent developments in transposon-mediated gene therapy.New developments in lentiviral vector design, production and purification.Immortalization of pig fibroblast cells by transposon-mediated ectopic expression of porcine telomerase reverse transcriptase Human somatic cell mutagenesis creates genetically tractable sarcomas.Sleeping Beauty transposition: from biology to applications.Sleeping Beauty-baculovirus hybrid vectors for long-term gene expression in the eye.Going non-viral: the Sleeping Beauty transposon system breaks on through to the clinical side.Development of hybrid baculovirus vectors for artificial MicroRNA delivery and prolonged gene suppression.

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P2860

Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

http://www.wikidata.org/entity/Q33713812

description

2009 nî lūn-bûn

@nan

2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

@zh-tw

2009年论文

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name

Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

@ast

Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

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type

label

Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

@ast

Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

@en

prefLabel

Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

@ast

Hybrid lentivirus-transposon vectors with a random integration profile in human cells.

@en

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P1433

Molecular Therapy

P1476

Hybrid lentivirus-transposon vectors with a random integration profile in human cells

@en

P2093

Brian Moldt

http://www.w3.org/2001/XMLSchema#string

Lajos Mátés

http://www.w3.org/2001/XMLSchema#string

Maria Jakobsen

http://www.w3.org/2001/XMLSchema#string

Zoltán Ivics

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Zsuzsanna Izsvák

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P2860

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

An essential role for LEDGF/p75 in HIV integration

High-resolution genome-wide mapping of transposon integration in mammals.

P304

1205-1214

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scholarly article

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10.1038/MT.2009.10

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7

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P478

17

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P50

Jacob Giehm Mikkelsen

Nicklas Heine Staunstrup

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2009-02-24T00:00:00Z

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24038143

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19240688

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P932

2835219

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