Repression of endogenous p53 transactivation function in HeLa cervical carcinoma cells by human papillomavirus type 16 E6, human mdm-2, and mutant p53
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A cellular defense pathway regulating transcription through poly(ADP-ribosyl)ation in response to DNA damageHIPK2 overexpression leads to stabilization of p53 protein and increased p53 transcriptional activity by decreasing Mdm2 protein levelsp53-independent endoplasmic reticulum stress-mediated cytotoxicity of a Newcastle disease virus strain in tumor cell linesNovel curcumin- and emodin-related compounds identified by in silico 2D/3D conformer screening induce apoptosis in tumor cellsUbiquitylation, phosphorylation and Orc2 modulate the subcellular location of Orc1 and prevent it from inducing apoptosisOverexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis.DeltaNp73alpha regulates MDR1 expression by inhibiting p53 function.NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner.Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint.Piwil2 suppresses p53 by inducing phosphorylation of signal transducer and activator of transcription 3 in tumor cellsDepletion of the histone chaperone tNASP inhibits proliferation and induces apoptosis in prostate cancer PC-3 cells.Dissecting the cell to nucleus, perinucleus and cytosol.p53 activates G₁ checkpoint following DNA damage by doxorubicin during transient mitotic arrest.MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagyCell type-specific inhibition of p53-mediated apoptosis by mdm2.A comprehensive analysis of radiosensitization targets; functional inhibition of DNA methyltransferase 3B radiosensitizes by disrupting DNA damage regulation.Natural variants of the human papillomavirus type 16 E6 protein differ in their abilities to alter keratinocyte differentiation and to induce p53 degradation.Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells.BUB1 mediation of caspase-independent mitotic death determines cell fate.Comparative analysis of p73 and p53 regulation and effector functions.Reversible repression of papillomavirus oncogene expression in cervical carcinoma cells: consequences for the phenotype and E6-p53 and E7-pRB interactionsTumor suppressor gene PDCD4 negatively regulates autophagy by inhibiting the expression of autophagy-related gene ATG5.Human papillomaviruses and cervical neoplasia. II. Interaction of HPV with other factors.Tumor cell survival dependence on the DHX9 DExH-box helicaseOverexpression of KLF4 promotes cell senescence through microRNA-203-survivin-p21 pathway.Transcriptional control of human papillomavirus (HPV) oncogene expression: composition of the HPV type 18 upstream regulatory region.Viral oncoproteins discriminate between p53 and the p53 homolog p73.Inhibition of p53-mediated transactivation by E6 of type 1, but not type 5, 8, or 47, human papillomavirus of cutaneous origin.Darinaparsin: solid tumor hypoxic cytotoxin and radiosensitizer.Nutlin-3 enhances the bortezomib sensitivity of p53-defective cancer cells by inducing paraptosis.Induction of p53-inducible microRNA miR-34 by gamma radiation and bleomycin are differentThe nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription.Dovitinib induces mitotic defects and activates the G2 DNA damage checkpoint.Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53.Correlation between tumorigenicity and expression levels or splicing patterns of transcripts of the human papillomavirus type 16 E6 gene.The transcription factor MEF/Elf4 is dually modulated by p53-MDM2 axis and MEF-MDM2 autoregulatory mechanism.Inherited DNA lesions determine G1 duration in the next cell cycle.Constitutive role of the Fanconi anemia D2 gene in the replication stress response.
P2860
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P2860
Repression of endogenous p53 transactivation function in HeLa cervical carcinoma cells by human papillomavirus type 16 E6, human mdm-2, and mutant p53
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Repression of endogenous p53 t ...... 6, human mdm-2, and mutant p53
@ast
Repression of endogenous p53 t ...... 6, human mdm-2, and mutant p53
@en
type
label
Repression of endogenous p53 t ...... 6, human mdm-2, and mutant p53
@ast
Repression of endogenous p53 t ...... 6, human mdm-2, and mutant p53
@en
prefLabel
Repression of endogenous p53 t ...... 6, human mdm-2, and mutant p53
@ast
Repression of endogenous p53 t ...... 6, human mdm-2, and mutant p53
@en
P2860
P1433
P1476
Repression of endogenous p53 t ...... 6, human mdm-2, and mutant p53
@en
P2093
F Hoppe-Seyler
P2860
P304
P407
P577
1993-06-01T00:00:00Z