Soluble and mature amyloid fibrils in drusen deposits - Wikidata - wikimedia - TriplyDB

Soluble and mature amyloid fibrils in drusen deposits

Soluble and mature amyloid fibrils in drusen deposits

http://www.wikidata.org/entity/Q33735695

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Therapeutic targets in age-related macular disease Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases Dementia of the eye: the role of amyloid beta in retinal degeneration NLRP3 inflammasome: activation and regulation in age-related macular degeneration The proteomics of drusen Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration Scotopic microperimetry in the early diagnosis of age-related macular degeneration: preliminary study.Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer's disease-linked presenilin 1 A246E mutation can be reversed with cAMP The complexities underlying age-related macular degeneration: could amyloid beta play an important role?Viewing ageing eyes: diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages.Iron increases APP translation and amyloid-beta production in the retina.Direct Interaction of Selenoprotein R with Clusterin and Its Possible Role in Alzheimer's Disease.Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells Age-Related Macular Degeneration: A Disease of Systemic or Local Complement Dysregulation?Amyloid β Peptide Induces Apoptosis Through P2X7 Cell Death Receptor in Retinal Cells: Modulation by Marine Omega-3 Fatty Acid DHA and EPA Cyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic mice Treatment of Stargardt disease with dobesilate.Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin Novel roles for α-crystallins in retinal function and disease.NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration Design and Optimization of Anti-amyloid Domain Antibodies Specific for β-Amyloid and Islet Amyloid Polypeptide Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: a novel culture model for dry AMD.Durable recovery of the macular architecture and functionality of a diagnosed age-related macular degeneration 1 year after a single intravitreal injection of dobesilate.Aging is not a disease: distinguishing age-related macular degeneration from aging.Nonvascular retinal imaging markers of preclinical Alzheimer's disease.SIRT1 negatively regulates amyloid-beta-induced inflammation via the NF-κB pathway.Dry age-related macular degeneration: mechanisms, therapeutic targets, and imaging.The Alzheimer's-related amyloid beta peptide is internalised by R28 neuroretinal cells and disrupts the microtubule associated protein 2 (MAP-2).Melatonin and abeta, macular degeneration and alzheimers disease: same disease, different outcomes?Disturbed Matrix Metalloproteinase Pathway in Both Age-Related Macular Degeneration and Alzheimer's Disease Inflammatory mediators induced by amyloid-beta in the retina and RPE in vivo: implications for inflammasome activation in age-related macular degeneration.The retina as a window to the brain-from eye research to CNS disorders.Electron microscopy: essentials for viral structure, morphogenesis and rapid diagnosis.Proteomic analysis of the aqueous humor in patients with wet age-related macular degeneration.Proteotoxicity and cardiac dysfunction.Structural, morphological, and functional diversity of amyloid oligomers.One protein, multiple pathologies: multifaceted involvement of amyloid β in neurodegenerative disorders of the brain and retina.Beta-amyloid sequelae in the eye: a critical review on its diagnostic significance and clinical relevance in Alzheimer's disease.

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P2860

Soluble and mature amyloid fibrils in drusen deposits

http://www.wikidata.org/entity/Q33735695

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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name

Soluble and mature amyloid fibrils in drusen deposits

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Soluble and mature amyloid fibrils in drusen deposits

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type

label

Soluble and mature amyloid fibrils in drusen deposits

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Soluble and mature amyloid fibrils in drusen deposits

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prefLabel

Soluble and mature amyloid fibrils in drusen deposits

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Soluble and mature amyloid fibrils in drusen deposits

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P1433

Investigative Ophthalmology & Visual Science

P1476

Soluble and mature amyloid fibrils in drusen deposits

@en

P2093

Charles G Glabe

http://www.w3.org/2001/XMLSchema#string

J Mario Isas

http://www.w3.org/2001/XMLSchema#string

Jeannie Chen

http://www.w3.org/2001/XMLSchema#string

Lincoln V Johnson

http://www.w3.org/2001/XMLSchema#string

Rakez Kayed

http://www.w3.org/2001/XMLSchema#string

Ralf Langen

http://www.w3.org/2001/XMLSchema#string

Ronald Wetzel

http://www.w3.org/2001/XMLSchema#string

Volker Luibl

http://www.w3.org/2001/XMLSchema#string

P2860

Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

Protein misfolding, evolution and disease

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

Complement factor H variant increases the risk of age-related macular degeneration

Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain

A specific amyloid-beta protein assembly in the brain impairs memory

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

Complement factor H polymorphism and age-related macular degeneration

Structural classification of toxic amyloid oligomers

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1304-1310

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scholarly article

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10.1167/IOVS.09-4207

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3

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51

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2009-11-05T00:00:00Z

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38070371

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19892876

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2840723

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