Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome - Wikidata - wikimedia - TriplyDB

Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome

Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome

http://www.wikidata.org/entity/Q33737846

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Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine Evaluating gene expression profiling by quantitative polymerase chain reaction to develop a clinically feasible test for outcome prediction in multiple myeloma Primary plasma cell leukemia 2.0: advances in biology and clinical management.Identification of novel pathogenic copy number aberrations in multiple myeloma: the Malaysian context Translating a gene expression signature for multiple myeloma prognosis into a robust high-throughput assay for clinical use.Genome-wide screening of cytogenetic abnormalities in multiple myeloma patients using array-CGH technique: a Czech multicenter experience.Implications of heterogeneity in multiple myeloma.WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.canEvolve: a web portal for integrative oncogenomics.CSNK1α1 mediates malignant plasma cell survival.A novel measure of chromosome instability can account for prognostic difference in multiple myeloma.The shaping and functional consequences of the dosage effect landscape in multiple myeloma.Expression profile of telomere-associated genes in multiple myeloma.Removing batch effects from purified plasma cell gene expression microarrays with modified ComBat.A gene expression based predictor for high risk myeloma treated with intensive therapy and autologous stem cell rescue.A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.European perspective on multiple myeloma treatment strategies: update following recent congresses Prediction of high- and low-risk multiple myeloma based on gene expression and the International Staging System.Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells.A gene expression-based predictor for myeloma patients at high risk of developing bone disease on bisphosphonate treatment.Expression and function of a novel isoform of Sox5 in malignant B cells.Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways.Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker.Multiple myeloma treatment strategies with novel agents in 2011: a European perspective The use of molecular-based risk stratification and pharmacogenomics for outcome prediction and personalized therapeutic management of multiple myeloma.Understanding the molecular biology of myeloma and its therapeutic implications.Bortezomib for the treatment of previously untreated multiple myeloma.Molecular profiling of multiple myeloma: from gene expression analysis to next-generation sequencing.IMWG consensus on risk stratification in multiple myeloma.Maintenance therapy in newly diagnosed multiple myeloma: current recommendations.Gene expression risk signatures maintain prognostic power in multiple myeloma despite microarray probe set translation.Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients.Current Review on High-Risk Multiple Myeloma.Mechanisms of Resistance in Multiple Myeloma.Gene signature combinations improve prognostic stratification of multiple myeloma patients.Multiple myeloma: so much progress, but so many unsolved questions.

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Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome

http://www.wikidata.org/entity/Q33737846

description

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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Clinical Cancer Research

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Homozygous deletion mapping in ...... nt to pathogenesis and outcome

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Athanasia Zeisig

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Brian A Walker

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David C Johnson

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David Gonzalez

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Faith E Davies

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Fiona M Ross

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Gareth J Morgan

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José L Brito

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P2860

Bioconductor: open software development for computational biology and bioinformatics

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

KEGG: kyoto encyclopedia of genes and genomes

Molecular inversion probes reveal patterns of 9p21 deletion and copy number aberrations in childhood leukemia

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

The Gene Ontology (GO) project: structured vocabularies for molecular biology and their application to genome and expression analysis.

dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data.

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

Distinctive gene expression patterns in human mammary epithelial cells and breast cancers.

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