Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity.
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Main roads to melanomaMitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreadingPhosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalitiesA comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromesNuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent mannerPTEN function: how normal cells control it and tumour cells lose itMale infertility, impaired spermatogenesis, and azoospermia in mice deficient for the pseudophosphatase Sbf1PTEN identified as important risk factor of chronic obstructive pulmonary diseaseCritical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformationChemoresistance in human ovarian cancer: the role of apoptotic regulatorsRetroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo.The PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.Drugging the addict: non-oncogene addiction as a target for cancer therapyDeubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesisTargeting mutants of PTEN reveal distinct subsets of tumour suppressor functionsNuclear PTEN levels and G2 progression in melanoma cellsDeriving cell lines from zebrafish embryos and tumorsPTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppressionPten regulates neuronal arborization and social interaction in mice.Subchronic exposure to arsenic through drinking water alters expression of cancer-related genes in rat liverRegulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein.PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7.Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancerExosome-mediated delivery of the intrinsic C-terminus domain of PTEN protects it from proteasomal degradation and ablates tumorigenesisCdc6 and cyclin E2 are PTEN-regulated genes associated with human prostate cancer metastasisThe role of PTEN in prostate cancer cell tropism to the bone micro-environment.Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of PtenPharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out miceAn optogenetic system for interrogating the temporal dynamics of Akt.A pharmacodynamic study of rapamycin in men with intermediate- to high-risk localized prostate cancer.Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons.Deregulation of FoxO3a accelerates prostate cancer progression in TRAMP miceMGMT promoter hypermethylation and K-RAS, PTEN and TP53 mutations in tamoxifen-exposed and non-exposed endometrial cancer casesThe role of PTEN tumor suppressor pathway staining in carcinoma in situ of the bladder.An integrative approach to identifying cancer chemoresistance-associated pathwaysPhosphoinositide phosphatases in cell biology and disease.An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice.
P2860
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P2860
Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mutational spectra of PTEN/MMA ...... th lipid phosphatase activity.
@ast
Mutational spectra of PTEN/MMA ...... th lipid phosphatase activity.
@en
type
label
Mutational spectra of PTEN/MMA ...... th lipid phosphatase activity.
@ast
Mutational spectra of PTEN/MMA ...... th lipid phosphatase activity.
@en
prefLabel
Mutational spectra of PTEN/MMA ...... th lipid phosphatase activity.
@ast
Mutational spectra of PTEN/MMA ...... th lipid phosphatase activity.
@en
P2093
P2860
P356
P1476
Mutational spectra of PTEN/MMA ...... th lipid phosphatase activity.
@en
P2093
P2860
P304
P356
10.1093/JNCI/91.22.1922
P407
P577
1999-11-01T00:00:00Z