Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis - Wikidata - wikimedia - TriplyDB

Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis

Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis

http://www.wikidata.org/entity/Q33782663

about

The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome Central and overlapping role of Cathepsin B and inflammasome adaptor ASC in antigen presenting function of human dendritic cells Control of innate and adaptive immunity by the inflammasome The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization The inflammasome NLRs in immunity, inflammation, and associated diseases P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/caspase 1 pathway.Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis.Apoptosis-associated speck-like protein (ASC) controls Legionella pneumophila infection in human monocytes.G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3 Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59.Inflammasomes and autoimmunity Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury.IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation.Significant role of IL-1 signaling, but limited role of inflammasome activation, in oviduct pathology during Chlamydia muridarum genital infection Inflammasome is a central player in the induction of obesity and insulin resistance.Targeting the inflammasome in rheumatic diseases.ASC deficiency suppresses proliferation and prevents medulloblastoma incidence Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.Toll-like receptor (TLR) and inflammasome actions in the central nervous system Enhanced activity of NLRP3 inflammasome in peripheral blood cells of patients with active rheumatoid arthritis.Spontaneous inflammatory pain model from a mouse line with N-ethyl-N-nitrosourea mutagenesis.Nucleosides accelerate inflammatory osteolysis, acting as distinct innate immune activators.NLRP3 Inflammasome Plays an Important Role in the Pathogenesis of Collagen-Induced Arthritis.Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis.Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines.Targeting inflammasomes in rheumatic diseases.Licensing Adaptive Immunity by NOD-Like Receptors.Hyperactivation of the NLRP3 Inflammasome in Myeloid Cells Leads to Severe Organ Damage in Experimental Lupus.A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte.Octacalcium phosphate crystals induce inflammation in vivo through interleukin-1 but independent of the NLRP3 inflammasome in mice.The emerging role of ASC in dendritic cell metabolism during Chlamydia infection.Role of inflammasomes in inflammatory autoimmune rheumatic diseases.Involvement of c-Abl Kinase in Microglial Activation of NLRP3 Inflammasome and Impairment in Autolysosomal System.ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis.

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P2860

Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis

http://www.wikidata.org/entity/Q33782663

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Inflammasome-independent role ...... for collagen-induced arthritis

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Inflammasome-independent role ...... for collagen-induced arthritis

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type

label

Inflammasome-independent role ...... for collagen-induced arthritis

@ast

Inflammasome-independent role ...... for collagen-induced arthritis

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prefLabel

Inflammasome-independent role ...... for collagen-induced arthritis

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Inflammasome-independent role ...... for collagen-induced arthritis

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JBC.M109.093252

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Journal of Biological Chemistry

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Inflammasome-independent role ...... for collagen-induced arthritis

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Christopher Calabrese

http://www.w3.org/2001/XMLSchema#string

Frank L Van de Veerdonk

http://www.w3.org/2001/XMLSchema#string

Jiwen Luo

http://www.w3.org/2001/XMLSchema#string

Kelli L Boyd

http://www.w3.org/2001/XMLSchema#string

Leo A B Joosten

http://www.w3.org/2001/XMLSchema#string

Mihai G Netea

http://www.w3.org/2001/XMLSchema#string

Mohamed Lamkanfi

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Rinke Stienstra

http://www.w3.org/2001/XMLSchema#string

P2860

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

The NLR gene family: a standard nomenclature

The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

The inflammasomes: guardians of the body

Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist.

Autoimmunity to type II collagen an experimental model of arthritis.

Granzyme A is an interleukin 1 beta-converting enzyme.

NALP3: a key player in caspase-1 activation.

Intracellular NOD-like receptors in host defense and disease.

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16

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285

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Thirumala-Devi Kanneganti

Sirish Kumar Ippagunta

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20177071

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