Src family tyrosine kinases and growth factor signaling.
about
Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signalingThe influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activationEphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxisBinding of Src to Na+/K+-ATPase forms a functional signaling complexSH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCFTwo adaptor proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by SRC kinaseThe molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targetsFunctional deregulation of KIT: link to mast cell proliferative diseases and other neoplasmsThe IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cellsDasatinib sensitizes KRAS mutant colorectal tumors to cetuximabTyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factorsTransformation of myeloid leukemia cells to cytokine independence by Bcr-Abl is suppressed by kinase-defective HckThe hunting of the SrcThe interaction of the Bcr-Abl tyrosine kinase with the Src kinase Hck is mediated by multiple binding domainsc-Src-dependent transcriptional activation of TFII-IRegulation of SRC family kinases in human cancersA Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian CancerTransforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cellsThe Activation of c-Src Tyrosine Kinase: Conformational Transition Pathway and Free Energy Landscape.Vinculin-p130Cas interaction is critical for focal adhesion dynamics and mechano-transduction.Substrate-specific reorganization of the conformational ensemble of CSK implicates novel modes of kinase functionProteins at work: a combined small angle X-RAY scattering and theoretical determination of the multiple structures involved on the protein kinase functional landscapeSrc kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets.Conformational basis for SH2-Tyr(P)527 binding in Src inactivation.Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activitiesActivation of STAT3 by the Src family kinase Hck requires a functional SH3 domain.Regulation of c-SRC activity and function by the adapter protein CASCytoplasmic death signal triggered by SRC-mediated phosphorylation of the adenovirus E4orf4 protein.The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recyclingIdentification of the SRC pyrimidine-binding protein (SPy) as hnRNP K: implications in the regulation of SRC1A transcriptionHydrogen peroxide induces Src family tyrosine kinase-dependent activation of Xenopus eggs.Off-target effects of BCR-ABL1 inhibitors and their potential long-term implications in patients with chronic myeloid leukemia.p66shc inhibits insulin-like growth factor-I signaling via direct binding to Src through its polyproline and Src homology 2 domains, resulting in impairment of Src kinase activation.Pyk2 activation triggers epidermal growth factor receptor signaling and cell motility after wounding sheets of epithelial cells.Practical management of patients with chronic myeloid leukemia.Adaptor protein Shc undergoes translocation and mediates up-regulation of the tyrosine kinase c-Src in EGF-stimulated A431 cells.Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases.Mechanisms of primary and secondary resistance to imatinib in chronic myeloid leukemia.Selected glimpses into the activation and function of Src kinase.pp60Src mediates insulin-stimulated sequestration of the beta(2)-adrenergic receptor: insulin stimulates pp60Src phosphorylation and activation.
P2860
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P2860
Src family tyrosine kinases and growth factor signaling.
description
2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
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2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Src family tyrosine kinases and growth factor signaling.
@ast
Src family tyrosine kinases and growth factor signaling.
@en
type
label
Src family tyrosine kinases and growth factor signaling.
@ast
Src family tyrosine kinases and growth factor signaling.
@en
prefLabel
Src family tyrosine kinases and growth factor signaling.
@ast
Src family tyrosine kinases and growth factor signaling.
@en
P356
P1476
Src family tyrosine kinases and growth factor signaling.
@en
P2093
Courtneidge SA
P356
10.1006/EXCR.1999.4732
P407
P577
2000-01-01T00:00:00Z