Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.
about
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activationCharacterization of an alternative splice variant of LKB1AMP-activated protein kinase, stress responses and cardiovascular diseasesHonokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesisRegulation and function of AMPK in physiology and diseasesAMPK: a cellular metabolic and redox sensor. A minireviewAtypical protein kinase C in cardiometabolic abnormalitiesThe orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPKArsenic inhibits neurite outgrowth by inhibiting the LKB1-AMPK signaling pathwayUncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAFPKC-dependent human monocyte adhesion requires AMPK and Syk activationEffect of ethanol on hydrogen peroxide-induced AMPK phosphorylationInhibitory effect of ethanol on AMPK phosphorylation is mediated in part through elevated ceramide levelsMechanism and role of high density lipoprotein-induced activation of AMP-activated protein kinase in endothelial cells.Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients.Convergence of IPMK and LKB1-AMPK signaling pathways on metformin action.AMPK-Dependent Metabolic Regulation by PPAR Agonists.Regulation of bile canalicular network formation and maintenance by AMP-activated protein kinase and LKB1.AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.Sepsis-induced alterations in protein-protein interactions within mTOR complex 1 and the modulating effect of leucine on muscle protein synthesisThe triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic-acid methyl ester has potent anti-diabetic effects in diet-induced diabetic mice and Lepr(db/db) miceMitigation of carbon tetrachloride-induced hepatic injury by methylene blue, a repurposed drug, is mediated by dual inhibition of GSK3β downstream of PKA.Red ginseng abrogates oxidative stress via mitochondria protection mediated by LKB1-AMPK pathwayProbucol suppresses human glioma cell proliferation in vitro via ROS production and LKB1-AMPK activationAnthocyanin inhibits high glucose-induced hepatic mtGPAT1 activation and prevents fatty acid synthesis through PKCζ.AMPK in cardiovascular health and disease.C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest.Up-regulation of AMP-activated protein kinase in cancer cell lines is mediated through c-Src activation.Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolismProtein kinase C beta mediates CD40 ligand-induced adhesion of monocytes to endothelial cells.Liver kinase B1 suppresses lipopolysaccharide-induced nuclear factor κB (NF-κB) activation in macrophagesImprovement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 miceAPPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathwayTargeting energy metabolic and oncogenic signaling pathways in triple-negative breast cancer by a novel adenosine monophosphate-activated protein kinase (AMPK) activatorCurcumin differentially regulates endoplasmic reticulum stress through transcriptional corepressor SMILE (small heterodimer partner-interacting leucine zipper protein)-mediated inhibition of CREBH (cAMP responsive element-binding protein H)Tyrosine nitration of prostacyclin synthase is associated with enhanced retinal cell apoptosis in diabetes.AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs.Mechanisms linking obesity, chronic kidney disease, and fatty liver disease: the roles of fetuin-A, adiponectin, and AMPK.Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality.Lipopolysaccharides Promote S-Nitrosylation and Proteasomal Degradation of Liver Kinase B1 (LKB1) in Macrophages in Vivo
P2860
Q24321658-12BB0734-470F-4581-9B75-300E53C94828Q24322647-80948B81-87B0-40B8-AC20-8D4CE1ED4CB3Q24610297-A38FDA6C-E4A2-47CD-B866-6BA02B1149A9Q24614006-590B0630-C164-4842-83CC-CBE1EF1C4F51Q26740291-034CF692-8C0F-46E9-95F6-1B8B60ACE26BQ26995682-3360A843-5349-4AB7-97EF-9D96FACF03FCQ27026092-122D1755-030D-4C55-B535-09F49CB694D6Q27682265-097778AB-A494-45F6-BC28-728E071252B5Q28395380-1205B56E-E179-4B3D-9A8D-6EC1D97BA5D9Q28474973-8BC18483-23A3-4E20-9388-2D80ECD6A1EBQ28481555-CFEA4AF4-35BD-4219-BBE5-2E686A1E62B8Q28569249-13D13921-9508-4A68-82DA-075FA2F24BE8Q28578006-91DB8E28-2FE0-4407-A138-5B4377EDB43FQ33717436-1EADA905-6668-488E-9F7D-C34F668B75BBQ33816483-1386FF1B-09AA-4A69-8D73-3EA30DBB44B6Q33821578-BE90A9FA-EC7B-4B9D-90DD-E2E0A6D4B964Q34089730-E7BE4F60-E33D-4B76-8B12-50AE69018B7AQ34129484-736F9FD2-79DB-49FD-8570-DEA754B64D7CQ34333672-3912CC45-5754-4C1C-A989-4E2B681516FDQ34372599-ACD39127-6558-4FA9-80E9-7B2F37EA8537Q34412580-BAE9B669-E644-41B6-80AF-033FA98B796BQ34570776-D05B7191-5458-4B21-BD26-5A9FAE342E97Q34626622-A2BAF520-8317-48E2-A753-552ADDDB28E5Q34664532-1660DEEA-C13F-4E19-B071-6060068ED894Q34776293-1D3734D6-3C63-43EE-9129-FE8B7656F6B7Q34807222-A017F486-64B3-4215-B91A-4DAB7DD8643DQ34852643-89C70374-A1E6-4778-907C-0FB182B05051Q34869734-02EB6571-96A7-4135-8C57-47FDFA36BD0BQ34966626-70A25AA0-9E6B-40AB-9473-C93F90F0BD8EQ34988499-1303EC8E-C787-495E-ACAE-F8207C4CBA6EQ35002962-81A5C62E-FFD3-49B0-973A-C0401D9B883BQ35043474-D0E3D25C-C3B8-418C-BDEB-674240D85FA0Q35238437-CF99D04A-7E5A-4220-8E22-0F4109D88565Q35604324-A1A5ED0B-05DF-4FA4-84B3-282B0100FCA5Q35605076-53EA5F27-DFA3-4F51-8845-ABA473BA63DDQ35679391-6B0F66A7-3D0E-4D5B-8775-DCCA3005F6A1Q35688331-C5246E45-017D-4F12-9C0B-9B9F2AB654DBQ35757790-F2C1EB67-6D4B-46E5-8C93-BFC6B39D9BA8Q35817986-4ACE7327-3771-4B00-A15F-EFFD1082060DQ35905322-BA7F7FCC-8644-4DA8-AA9C-D2B9C43CDC51
P2860
Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Phosphorylation of LKB1 at ser ...... n kinase in endothelial cells.
@ast
Phosphorylation of LKB1 at ser ...... n kinase in endothelial cells.
@en
type
label
Phosphorylation of LKB1 at ser ...... n kinase in endothelial cells.
@ast
Phosphorylation of LKB1 at ser ...... n kinase in endothelial cells.
@en
prefLabel
Phosphorylation of LKB1 at ser ...... n kinase in endothelial cells.
@ast
Phosphorylation of LKB1 at ser ...... n kinase in endothelial cells.
@en
P2093
P2860
P921
P1433
P1476
Phosphorylation of LKB1 at ser ...... in kinase in endothelial cells
@en
P2093
Ming-Hui Zou
Yunzhou Dong
Zhonglin Xie
P2860
P304
P356
10.1161/CIRCULATIONAHA.107.744490
P407
P577
2008-02-04T00:00:00Z