The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage.
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Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine.Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleusMapping of key functions of the herpes simplex virus 1 U(S)3 protein kinase: the U(S)3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptidesThe interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathwaysBovine Herpes Virus 1 (BHV-1) and Herpes Simplex Virus Type 1 (HSV-1) Promote Survival of Latently Infected Sensory Neurons, in Part by Inhibiting ApoptosisImproper tagging of the non-essential small capsid protein VP26 impairs nuclear capsid egress of herpes simplex virus.Alphaherpesvirus infection disrupts mitochondrial transport in neuronsEffects of phosphorylation of herpes simplex virus 1 envelope glycoprotein B by Us3 kinase in vivo and in vitroPlus- and minus-end directed microtubule motors bind simultaneously to herpes simplex virus capsids using different inner tegument structuresTowards an understanding of the herpes simplex virus type 1 latency-reactivation cycleHerpes simplex virus protein kinases US3 and UL13 modulate VP11/12 phosphorylation, virion packaging, and phosphatidylinositol 3-kinase/Akt signaling activityThe suppression of apoptosis by α-herpesvirus.The domains of glycoprotein D required to block apoptosis depend on whether glycoprotein D is present in the virions carrying herpes simplex virus 1 genome lacking the gene encoding the glycoprotein.Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functionsThe US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins.T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infectionInterwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genesHerpes simplex virus 1-encoded protein kinase UL13 phosphorylates viral Us3 protein kinase and regulates nuclear localization of viral envelopment factors UL34 and UL31An early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0.U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner.Ultrastructural localization of the herpes simplex virus type 1 UL31, UL34, and US3 proteins suggests specific roles in primary envelopment and egress of nucleocapsids.Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1U(S)3 and U(S)3.5 protein kinases of herpes simplex virus 1 differ with respect to their functions in blocking apoptosis and in virion maturation and egress.ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression.Infection of cattle with a bovine herpesvirus 1 strain that contains a mutation in the latency-related gene leads to increased apoptosis in trigeminal ganglia during the transition from acute infection to latency.Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cellsThe herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BADHerpes simplex virus type 1 and bovine herpesvirus 1 latency.ORF66 protein kinase function is required for T-cell tropism of varicella-zoster virus in vivoHerpes simplex virus 1 protein kinase Us3 and major tegument protein UL47 reciprocally regulate their subcellular localization in infected cells.US3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with programmed cell death protein 4 (PDCD4) to block apoptosisHerpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosisHerpes simplex virus infection and apoptosis.Glycoprotein M of herpes simplex virus 1 is incorporated into virions during budding at the inner nuclear membrane.Phylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells.The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions.Apoptosis and antigen receptor function in T and B cells following exposure to herpes simplex virusBcl-2 blocks accretion or depletion of stored calcium but has no effect on the redistribution of IP3 receptor I mediated by glycoprotein E of herpes simplex virus 1.In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3.Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase.
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P2860
The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage.
description
2001 nî lūn-bûn
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2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The U(S)3 protein kinase block ...... 1 at a premitochondrial stage.
@ast
The U(S)3 protein kinase block ...... 1 at a premitochondrial stage.
@en
type
label
The U(S)3 protein kinase block ...... 1 at a premitochondrial stage.
@ast
The U(S)3 protein kinase block ...... 1 at a premitochondrial stage.
@en
prefLabel
The U(S)3 protein kinase block ...... 1 at a premitochondrial stage.
@ast
The U(S)3 protein kinase block ...... 1 at a premitochondrial stage.
@en
P2860
P1433
P1476
The U(S)3 protein kinase block ...... 1 at a premitochondrial stage.
@en
P2093
P2860
P304
P356
10.1128/JVI.75.12.5491-5497.2001
P577
2001-06-01T00:00:00Z